{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T11:48:39Z","timestamp":1792756119524,"version":"4.5.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,9,15]],"date-time":"2015-09-15T00:00:00Z","timestamp":1442275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>The prevalence of chronic disease and do-not-intubate status increases with age. Thus, we aimed to determine characteristics and outcomes associated with noninvasive ventilation (NIV) use for acute respiratory failure (ARF) in different age groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A database comprising prospective data collected on site on all adult patients with ARF requiring ventilatory support from 8 acute care hospitals in Massachusetts was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      From a total of 1,225 ventilator starts, overall NIV utilization, success, and in-hospital mortality rates were 22, 54, and 18% in younger (18\u201344 y); 34, 65, and 13% in middle-aged (45\u201364 y); 49, 68, and 17% in elderly (65\u201379 y); and 47, 76, and 24% in aged (\u226580 y) groups, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .08, and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .11, respectively). NIV use for cardiogenic pulmonary edema and subjects with a do-not-intubate order increased significantly with advancing age (25, 57, 57, and 74% and 7, 12, 18, and 31%, respectively, in the 4 age groups [\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .046, respectively]). For subjects receiving NIV with a do-not-intubate order, success and in-hospital mortality rates were similar in different age groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .27 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .98, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>NIV use and a do-not-intubate status are more frequent in subjects with ARF \u226565 y than in those &lt;65 y, especially for subjects with cardiogenic pulmonary edema. However, NIV success and mortality rates were similar between age groups. (ClinicalTrials.gov registration NCT00458926.)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.03966","type":"journal-article","created":{"date-parts":[[2015,9,15]],"date-time":"2015-09-15T21:53:53Z","timestamp":1442354033000},"page":"36-43","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Use and Outcomes of Noninvasive Ventilation for Acute Respiratory Failure in Different Age Groups"],"prefix":"10.1177","volume":"61","author":[{"given":"Aylin","family":"Ozsancak Ugurlu","sequence":"first","affiliation":[{"name":"Department of Pulmonary Disease, Baskent University, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samy S","family":"Sidhom","sequence":"additional","affiliation":[{"name":"Pulmonary Department, Newton-Wellesley Hospital, Newton, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Khodabandeh","sequence":"additional","affiliation":[{"name":"Mass Lung and Allergy PC, Leominster, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ieong","sequence":"additional","affiliation":[{"name":"Boston Medical Center, Boston, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chester","family":"Mohr","sequence":"additional","affiliation":[{"name":"Cape Cod Health Systems, Hyannis, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis Y","family":"Lin","sequence":"additional","affiliation":[{"name":"Lowell General Hospital, Lowell, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irwin","family":"Buchwald","sequence":"additional","affiliation":[{"name":"Saints Medical Center, Lowell, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imad","family":"Bahhady","sequence":"additional","affiliation":[{"name":"Steward Morton Hospital, Taunton, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Wengryn","sequence":"additional","affiliation":[{"name":"Jordan Hospital, Plymouth, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Maheshwari","sequence":"additional","affiliation":[{"name":"Pulmonary Associates, Newark, Delaware."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas S","family":"Hill","sequence":"additional","affiliation":[{"name":"Department of Pulmonary, Critical Care, and Sleep Medicine, Tufts Medical Center, Boston, Massachusetts."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,9,15]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1197"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/jhm.2004"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-015-0094-2"},{"issue":"4","key":"e_1_3_3_5_2","first-page":"797","article-title":"Effect of noninvasive mechanical ventilation in elderly patients with hypercapnic acute-on-chronic respiratory failure and a do-not-intubate order","volume":"3","author":"Scarpazza P","year":"2008","unstructured":"Scarpazza P, , Incorvaia C, , di Franco G, , Raschi S, , Usai P, , Bernareggi M, et al. Effect of noninvasive mechanical ventilation in elderly patients with hypercapnic acute-on-chronic respiratory failure and a do-not-intubate order. 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Mechanical ventilation in elderly patients. Monaldi Arch Chest Dis, 1998; 53(5):547\u2013551.","journal-title":"Monaldi Arch Chest Dis"},{"key":"e_1_3_3_17_2","unstructured":"Centers for Disease Control and Prevention. International Classification of Diseases Ninth Revision Clinical Modification (ICD-9-CM). http:\/\/www.cdc.gov\/nchs\/icd\/icd9cm.htm. 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