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We present the cases of 5 infants treated for acute bronchiolitis with respiratory distress using a combination of high-flow nasal cannula oxygen (HFNC) and an Aerogen nebulizer to deliver aerosolized \u03b2-agonist therapy. In all infants, we found that HFNC resulted in a greater heart rate increase than delivery via a facemask. We also found that patients tolerated inhaled therapy better with HFNC than a facemask.<\/jats:p>","DOI":"10.4187\/respcare.03996","type":"journal-article","created":{"date-parts":[[2015,6,23]],"date-time":"2015-06-23T21:15:27Z","timestamp":1435094127000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":34,"title":["High-Flow Nasal Cannula and Aerosolized \u03b2 Agonists for Rescue Therapy in Children With Bronchiolitis: A Case Series"],"prefix":"10.1177","volume":"60","author":[{"given":"Sherwin E","family":"Morgan","sequence":"first","affiliation":[{"name":"Department of Respiratory Care"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Mosakowski","sequence":"additional","affiliation":[{"name":"Department of Respiratory Care"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patti","family":"Solano","sequence":"additional","affiliation":[{"name":"Department of Respiratory Care"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse B","family":"Hall","sequence":"additional","affiliation":[{"name":"Section of Pulmonary and Critical Care Medicine, Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avery","family":"Tung","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care, The University of Chicago, Chicago, Illinois."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,9,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.10.039"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02728"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-2742"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.2015.1.24930"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/002013240004500608"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1972.02110090097011"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2743-5"},{"key":"e_1_3_2_9_2","first-page":"CD006405","article-title":"High flow nasal cannula for respiratory support in preterm infants","volume":"5","author":"Wilkinson D","year":"2011","unstructured":"Wilkinson D, , Andersen C, , O'Donnell CP, , De Paoli AG. 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