{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T18:08:55Z","timestamp":1784311735758,"version":"3.55.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T00:00:00Z","timestamp":1451347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2016,4]]},"abstract":"\n BACKGROUND:<\/jats:title>\n Measurement of oxygen saturation with a handheld pulse oximeter is widely practiced as a surrogate to invasive arterial blood gas analysis. Oxygen saturation is an important parameter in cases of COPD, but there are insufficient data on the role of pulse oximetry in patients with COPD, moreso in diseases across its spectrum, such as chronic bronchitis and emphysema. We assessed the performance of pulse oximetry in acute respiratory failure of patients with COPD.<\/jats:p>\n <\/jats:sec>\n \n METHODS:<\/jats:title>\n \n This was a cross-sectional, observational study. We studied 50 subjects with COPD admitted to the Government General Hospital, a 1,000-bed tertiary referral center in Guntur, India, from June 2013 to July 2013. Simultaneous reading of S\n \n pO\n 2<\/jats:sub>\n <\/jats:sub>\n by a handheld pulse oximeter and S\n \n aO\n 2<\/jats:sub>\n <\/jats:sub>\n by an automated arterial blood gas analyzer were taken.\n <\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n \n Pulse oximetry was sufficiently sensitive (84.60%) to hypoxemia in respiratory failure to be used in clinical situations. The mean difference (bias) between S\n \n aO\n 2<\/jats:sub>\n <\/jats:sub>\n and S\n \n pO\n 2<\/jats:sub>\n <\/jats:sub>\n was \u22123.98 (95% CI \u22124.68 to 3.28). There was less sensitivity (82% vs 85%) and positive predictive value (69% vs 85%) of the pulse oximeter to respiratory failure in subjects with chronic bronchitis versus emphysema.\n <\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Pulse oximetry performed poorly in comparison with the invasive arterial blood gas analysis. The variability of the readings was greater in the subjects with chronic bronchitis than in those with emphysema.<\/jats:p>\n <\/jats:sec>","DOI":"10.4187\/respcare.04435","type":"journal-article","created":{"date-parts":[[2015,12,29]],"date-time":"2015-12-29T22:03:55Z","timestamp":1451426635000},"page":"423-427","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":44,"title":["Pulse Oximetry Overestimates Oxygen Saturation in COPD"],"prefix":"10.1177","volume":"61","author":[{"given":"Sridhar","family":"Amalakanti","sequence":"first","affiliation":[{"name":"Department of Neurology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohan Rao","family":"Pentakota","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Guntur Medical College, Guntur, India."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,12,29]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000104812"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc2339"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2002.32252"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001340101064"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201204-0596PP"},{"issue":"5","key":"e_1_3_3_7_2","first-page":"762","article-title":"Chronic bronchitis, asthma, and pulmonary emphysema: a statement by Committee on Diagnostic Standards for Nontuberculous Respiratory Diseases","volume":"85","author":"Meneely GR","year":"1962","unstructured":"Meneely GR, , Wyatt JP, , Steele JD, , Renzetti AD, , Harris HW. Chronic bronchitis, asthma, and pulmonary emphysema: a statement by Committee on Diagnostic Standards for Nontuberculous Respiratory Diseases. Am Rev Respir Dis, 1962; 85(5):762\u2013763.","journal-title":"Am Rev Respir Dis"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2007.10.019"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.5.9903015"},{"issue":"6","key":"e_1_3_3_10_2","first-page":"587","article-title":"Ethical guidelines for biomedical research on human participants","volume":"126","author":"Bhattacharya SK","year":"2007","unstructured":"Bhattacharya SK, , Sur D. Ethical guidelines for biomedical research on human participants. 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Can Respir J, 2013; 20(4):259\u2013261.","journal-title":"Can Respir J"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2659-0"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.111393"},{"issue":"4","key":"e_1_3_3_16_2","first-page":"479","article-title":"Accuracy of a pulse oximeter during hypoxia","volume":"45","author":"Tachibana C","year":"1996","unstructured":"Tachibana C, , Fukada T, , Hasegawa R, , Satoh K, , Furuya Y, , Ohe Y. Accuracy of a pulse oximeter during hypoxia. Masui, 1996; 45(4):479\u2013482.","journal-title":"Masui"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01690773"},{"issue":"6","key":"e_1_3_3_18_2","first-page":"194","article-title":"Limitations of pulse oximetry","volume":"39","author":"Mardirossian G","year":"1992","unstructured":"Mardirossian G, , Schneider RE. Limitations of pulse oximetry. Anesth Prog, 1992; 39(6):194\u2013196.","journal-title":"Anesth Prog"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.5.1244"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0004-9514(14)61155-7"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.04435","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.04435","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.04435","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:17:41Z","timestamp":1777616261000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.04435"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,29]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.4187\/respcare.04435"],"URL":"https:\/\/doi.org\/10.4187\/respcare.04435","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12,29]]}}}