{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T21:21:00Z","timestamp":1789852860544,"version":"4.0.1"},"reference-count":33,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2016,8,30]],"date-time":"2016-08-30T00:00:00Z","timestamp":1472515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Respiratory complications remain a major cause of mortality among individuals with spinal-cord injury (SCI). The present study investigated whether respiratory function is a discriminator of pneumonia in individuals with SCI and is aimed to determine the best predictive parameter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      This was a retrospective cohort study. Individuals with traumatic SCI, level C3 to T12, complete and incomplete lesions, were included. Data on respiratory function were extracted from medical records. The receiver operating characteristic curve was calculated for each parameter (forced vital capacity, FEV\n                      <jats:sub>1<\/jats:sub>\n                      , peak expiratory flow, and maximum inspiratory and expiratory pressure [P\n                      <jats:sub>Imax<\/jats:sub>\n                      and P\n                      <jats:sub>Emax<\/jats:sub>\n                      ]) to determine the discriminator with the largest area under the curve between individuals with and without pneumonia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Data of 307 subjects were analyzed. P\n                      <jats:sub>Imax<\/jats:sub>\n                      was identified as the best discriminator between individuals with and without pneumonia, both in motor complete (area under the curve 0.86, 95% CI 0.78\u20130.93,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and incomplete individuals (area under the curve 1.0, 95% CI 1.00\u20131.00,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). In individuals with motor complete lesions, the threshold value for P\n                      <jats:sub>Imax<\/jats:sub>\n                      was 115% of the lesion-specific reference value (sensitivity 74.4%, specificity 83.4%). In motor incomplete individuals, the P\n                      <jats:sub>Imax<\/jats:sub>\n                      threshold value was 93.5 cm H\n                      <jats:sub>2<\/jats:sub>\n                      O (sensitivity 100%, specificity 100%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>\n                      P\n                      <jats:sub>Imax<\/jats:sub>\n                      is the best discriminator between spinal cord-injured individuals with versus those without pneumonia. Individuals with a P\n                      <jats:sub>Imax<\/jats:sub>\n                      below threshold values are at risk of pneumonia.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.04818","type":"journal-article","created":{"date-parts":[[2016,8,30]],"date-time":"2016-08-30T22:23:53Z","timestamp":1472595833000},"page":"1636-1643","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Maximum Inspiratory Pressure is a Discriminator of Pneumonia in Individuals With Spinal-Cord Injury"],"prefix":"10.1177","volume":"61","author":[{"given":"Anja M","family":"Raab","sequence":"first","affiliation":[{"name":"Clinical Trial Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Krebs","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Perret","sequence":"additional","affiliation":[{"name":"Institute of Sports Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Michel","sequence":"additional","affiliation":[{"name":"Ambulatory Services, Swiss Paraplegic Centre, Nottwil, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria TE","family":"Hopman","sequence":"additional","affiliation":[{"name":"Department of Physiology, Radboud University Nijmegen, Nijmegen, The Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabi","family":"Mueller","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,8,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-014-9575-8"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.4045\/tidsskr.10.0922"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1179\/2045772314Y.0000000254"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2014.28"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0812"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0017"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.phm.0000223403.94148.67"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3171\/2012.4.AOSPINE1295"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1548"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313480106700201"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0410"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2010.172"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-1011"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-9651(18)30145-1"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.18773\/austprescr.2003.082"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1179\/2045772314Y.0000000254"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2013.77"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.3171\/2012.5.AOSPINE12127"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/10790268.2007.11753946"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198708000-00010"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01376517-199804000-00003"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e3181ddca8e"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2013.02.006"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-1097"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101835"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200112151-00006"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.85.6.792"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.99.6.1485"},{"key":"e_1_3_3_30_2","first-page":"335","volume-title":"Handbook of Clinical Neurology","author":"Fugl-Meyer AR","year":"1976","unstructured":"Fugl-Meyer AR. The respiratory system. In: Vinken PJ, , Bruyn GW, editors. Handbook of Clinical Neurology. Vol. 26. New York: American Elsevier; 1976:335\u2013349."},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.118.1.61"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/168757"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2013.162"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-0162"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.04818","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.04818","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.04818","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:19:04Z","timestamp":1777616344000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.04818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,30]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.4187\/respcare.04818"],"URL":"https:\/\/doi.org\/10.4187\/respcare.04818","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8,30]]}}}