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Consequently, obese patients may be particularly predisposed to the development of respiratory muscle fatigue during exercise. The aim of this study was to assess inspiratory muscle performance during incremental exercise in 19 obese male subjects (body mass index 41 \u00b1 6 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ) after aerobic exercise training using the noninvasive, inspiratory muscle tension-time index (T\n                      <jats:sub>T0.1<\/jats:sub>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      Measurements performed included anthropometric parameters, lung function assessed by spirometry, rate of perceived breathlessness with the modified Borg dyspnea scale (0\u201310), breathing pattern, maximal exercise capacity, and inspiratory muscle performance with a breath-by-breath automated exercise metabolic system during an incremental exercise test. T\n                      <jats:sub>T0.1<\/jats:sub>\n                      was calculated using the equation, T\n                      <jats:sub>T0.1<\/jats:sub>\n                      = P\n                      <jats:sub>0.1<\/jats:sub>\n                      \/P\n                      <jats:sub>Imax<\/jats:sub>\n                      \u00d7 T\n                      <jats:sub>I<\/jats:sub>\n                      \/T\n                      <jats:sub>tot<\/jats:sub>\n                      (where P\n                      <jats:sub>0.1<\/jats:sub>\n                      represents mouth occlusion pressure, P\n                      <jats:sub>Imax<\/jats:sub>\n                      is maximal inspiratory pressure, and T\n                      <jats:sub>I<\/jats:sub>\n                      \/T\n                      <jats:sub>tot<\/jats:sub>\n                      is the duty cycle).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      At rest, there was no statistically significant difference for spirometric parameters and cardiorespiratory parameters between pre- and post-training. At maximal exercise, the minute ventilation, the rate of exchange ratio, the rate of perceived breathlessness, and the respiratory muscle performance parameters were not significantly different pre- and post-training; in contrast, tidal volume (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .037, effect size = 1.51), breathing frequency (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .049, effect size = 0.97), power output (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .048, effect size = 0.79), peak oxygen uptake (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .02, effect size = 0.92) were significantly higher after training. At comparable work load, training induces lower minute ventilation, mouth occlusion pressure, ratio of occlusion pressure to maximal inspiratory pressure, T\n                      <jats:sub>T0.1<\/jats:sub>\n                      , and rate of perceived breathlessness.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Aerobic exercise at ventilatory threshold can induce significant improvement in respiratory muscle strength, maximal exercise capacity, and inspiratory muscle performance and decreased dyspnea perception in obese subjects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.04923","type":"journal-article","created":{"date-parts":[[2017,4,25]],"date-time":"2017-04-25T20:40:25Z","timestamp":1493152825000},"page":"936-946","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":34,"title":["Effect of Aerobic Exercise Training on Ventilatory Efficiency and Respiratory Drive in Obese Subjects"],"prefix":"10.1177","volume":"62","author":[{"given":"Mehdi","family":"Chlif","sequence":"first","affiliation":[{"name":"EA-3300 :APERE, Exercise Physiology and Rehabilitation Laboratory, Picardie Jules Verne University, Sport Sciences Department, Avenue Paul Claudel, F-80025, Amiens Cedex, France."},{"name":"Tunisian Research Laboratory \u201cSport Performance Optimisation\u201d, National Center of Medicine and Science in Sports (CNMSS), Tunis, Tunisia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anis","family":"Chaouachi","sequence":"additional","affiliation":[{"name":"Tunisian Research Laboratory \u201cSport Performance Optimisation\u201d, National Center of Medicine and Science in Sports (CNMSS), Tunis, Tunisia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Ahmaidi","sequence":"additional","affiliation":[{"name":"EA-3300 :APERE, Exercise Physiology and Rehabilitation Laboratory, Picardie Jules Verne University, Sport Sciences Department, Avenue Paul Claudel, F-80025, Amiens Cedex, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,4,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199901001-00003"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2013.05.019"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803546"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2011.02096.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2011.02124.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1123\/pes.19.1.82"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1233486"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803030"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2012.08.001"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200104000-00006"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1984.129.2P2.S90"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.166.4.518"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.6.9912053"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200029060-00001"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.08.020"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201402-0337ST"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.071480"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.061648"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"issue":"3","key":"e_1_3_3_21_2","first-page":"401","article-title":"Prediction equations for forced spirometry from European origin populations. 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