{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:55:58Z","timestamp":1775469358565,"version":"3.50.1"},"reference-count":61,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,12,6]],"date-time":"2016-12-06T00:00:00Z","timestamp":1480982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Computerized respiratory sounds are a simple and noninvasive measure to assess lung function. Nevertheless, their potential to detect changes after pulmonary rehabilitation (PR) is unknown and needs clarification if respiratory acoustics are to be used in clinical practice. Thus, this study investigated the short- and mid-term effects of PR on computerized respiratory sounds in subjects with COPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      Forty-one subjects with COPD completed a 12-week PR program and a 3-month follow-up. Secondary outcome measures included dyspnea, self-reported sputum, FEV\n                      <jats:sub>1<\/jats:sub>\n                      , exercise tolerance, self-reported physical activity, health-related quality of life, and peripheral muscle strength. Computerized respiratory sounds, the primary outcomes, were recorded at right\/left posterior chest using 2 stethoscopes. Air flow was recorded with a pneumotachograph. Normal respiratory sounds, crackles, and wheezes were analyzed with validated algorithms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      There was a significant effect over time in all secondary outcomes, with the exception of FEV\n                      <jats:sub>1<\/jats:sub>\n                      and of the impact domain of the St George Respiratory Questionnaire. Inspiratory and expiratory median frequencies of normal respiratory sounds in the 100\u2013300 Hz band were significantly lower immediately (\u22122.3 Hz [95% CI \u22124 to \u22120.7] and \u22121.9 Hz [95% CI \u22123.3 to \u22120.5]) and at 3 months (\u22122.1 Hz [95% CI \u22123.6 to \u22120.7] and \u22122 Hz [95% CI \u22123.6 to \u22120.5]) post-PR. The mean number of expiratory crackles (\u22120.8, 95% CI \u22121.3 to \u22120.3) and inspiratory wheeze occupation rate (median 5.9 vs 0) were significantly lower immediately post-PR.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Computerized respiratory sounds were sensitive to short- and mid-term effects of PR in subjects with COPD. These findings are encouraging for the clinical use of respiratory acoustics. Future research is needed to strengthen these findings and explore the potential of computerized respiratory sounds to assess the effectiveness of other clinical interventions in COPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.04987","type":"journal-article","created":{"date-parts":[[2016,12,6]],"date-time":"2016-12-06T20:40:29Z","timestamp":1481056829000},"page":"199-208","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Computerized Respiratory Sounds: Novel Outcomes for Pulmonary Rehabilitation in COPD"],"prefix":"10.1177","volume":"62","author":[{"given":"Cristina","family":"J\u00e1come","sequence":"first","affiliation":[{"name":"Research Centre in Physical Activity, Health, and Leisure (CIAFEL), Faculty of Sports, University of Porto, Porto, Portugal and Lab 3R, Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alda","family":"Marques","sequence":"additional","affiliation":[{"name":"Lab 3R, Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Aveiro, Portugal and the Institute for Research in Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,12,6]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. 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