{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T23:10:06Z","timestamp":1783725006733,"version":"3.55.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>The population of children requiring home mechanical ventilation has evolved over the years and has grown to include a variety of diagnoses and needs that have led to changes in the care of this unique population. The purpose of this study was to provide a descriptive analysis of pediatric patients requiring home mechanical ventilation after hospitalization and how the evolution of this technology has impacted their care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A retrospective, observational, longitudinal analysis of 164 children enrolled in a university-affiliated home mechanical ventilation program over 26 years was performed. Data included each child's primary diagnosis, date of tracheostomy placement, duration of mechanical ventilation during hospitalization that consisted of home mechanical ventilator initiation, total length of pediatric ICU stay, ventilator settings at time of discharge from pediatric ICU, and disposition (home, facility, or died). Univariate, bivariate, and regression analysis was used as appropriate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The most common diagnosis requiring the use of home mechanical ventilation was neuromuscular disease (53%), followed by chronic pulmonary disease (29%). The median length of stay in the pediatric ICU decreased significantly after the implementation of a ventilator ward (70 d [30\u2013142] vs 36 d [18\u201367],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .02). The distribution of subjects upon discharge was home (71%), skilled nursing facility (24%), and died (4%), with an increase in the proportion of subjects discharged on PEEP and those going to nursing facilities over time (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The evolution of home mechanical ventilation has allowed earlier transition out of the pediatric ICU and with increasing disposition to skilled nursing facilities over time. There has also been a change in ventilator management, including increased use of PEEP upon discharge, possibly driven by changes in ventilators and in-patient practice patterns.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.05644","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T20:35:16Z","timestamp":1520368516000},"page":"558-564","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":39,"title":["Analysis of a Pediatric Home Mechanical Ventilator Population"],"prefix":"10.1177","volume":"63","author":[{"given":"Rambod","family":"Amirnovin","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Aghamohammadi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Critical Care Medicine, University of California Davis, Sacramento."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carley","family":"Riley","sequence":"additional","affiliation":[{"name":"Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlyn S","family":"Woo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology and Sleep Medicine, University of California Los Angeles Mattel Children's Hospital, UCLA David Geffen School of Medicine, Los Angeles."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Del Castillo","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,3,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2471"},{"issue":"1","key":"e_1_3_3_3_2","first-page":"258","article-title":"Home mechanical ventilation of pediatric patients","volume":"141","author":"Eigenn H","year":"1990","unstructured":"Eigenn H, , Zander J. Home mechanical ventilation of pediatric patients. Am J Respir Crit Care Med, 1990; 141(1):258\u2013259.","journal-title":"Am J Respir Crit Care Med"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000298641.84257.53"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2007.02463.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)36180-6"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.157"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.2.257"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21371"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2002.019562"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1996.tb03456.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22868"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hch087"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/000992289303201201"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1084-2756(02)00220-8"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2005.00753.x"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2545-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2009.01618.x"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.06.012"},{"issue":"1","key":"e_1_3_3_20_2","first-page":"43","article-title":"The ventilator-dependent child: issues in diagnosis and management","volume":"72","author":"Mallory GB","year":"1991","unstructured":"Mallory GBJr, , Stillwell PC. The ventilator-dependent child: issues in diagnosis and management. Arch Phys Med Rehabil, 1991; 72(1):43\u201355.","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"e_1_3_3_21_2","first-page":"131","article-title":"Technology-dependent children in New York state","volume":"67","author":"Millner BN","year":"1991","unstructured":"Millner BN. Technology-dependent children in New York state. Bull N Y Acad Med, 1991; 67(2):131\u2013142.","journal-title":"Bull N Y Acad Med"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21214"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.NHH.0000343784.88852.94"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/NHH.0b013e3182429243"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.7748\/paed2008.02.20.1.14.c6351"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.5.1560"},{"issue":"1","key":"e_1_3_3_27_2","first-page":"48","article-title":"Families with a ventilator-assisted child: transitional issues","volume":"14","author":"Allen NL","year":"1994","unstructured":"Allen NL, , Simone JA, , Wingenbach GF. Families with a ventilator-assisted child: transitional issues. J Perinatol, 1994; 14(1):48\u201355.","journal-title":"J Perinatol"},{"issue":"3","key":"e_1_3_3_28_2","first-page":"432","article-title":"Psychosocial concerns of the ventilator-dependent child in the pediatric intensive care unit","volume":"2","author":"Warner J","year":"1991","unstructured":"Warner J, , Norwood S. Psychosocial concerns of the ventilator-dependent child in the pediatric intensive care unit. AACN Clin Issues Crit Care Nurs, 1991; 2(3):432\u2013445.","journal-title":"AACN Clin Issues Crit Care Nurs"},{"issue":"2","key":"e_1_3_3_29_2","first-page":"S36","article-title":"Long-term mechanical ventilation in pediatric respiratory failure: medical and ethical considerations","volume":"140","author":"Farrell PM","year":"1989","unstructured":"Farrell PM, , Fost NC. Long-term mechanical ventilation in pediatric respiratory failure: medical and ethical considerations. Am J Respir Crit Care Med, 1989; 140(2 Pt 2):S36\u2013S40.","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.05644","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.05644","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.05644","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T11:08:28Z","timestamp":1775473708000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.05644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,6]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["10.4187\/respcare.05644"],"URL":"https:\/\/doi.org\/10.4187\/respcare.05644","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3,6]]}}}