{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T06:24:18Z","timestamp":1775715858416,"version":"3.50.1"},"reference-count":25,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T00:00:00Z","timestamp":1506384000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Noninvasive ventilation (NIV) has proven to be useful in the management of children with acute respiratory failure as a result of acute lower respiratory infection. Despite this, evidence addressing the initiation and\/or discontinuation criteria of NIV in children remains limited. The objective of this study was to evaluate the usefulness and clinical impact of an NIV protocol in hospitalized children with acute respiratory failure because of acute lower respiratory infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A randomized controlled clinical trial was carried out among subjects admitted during the winter season at Hospital Josefina Martinez between May and October of 2013. Inclusion criteria were age 3 months to 2 y, diagnosis of acute lower respiratory infection and requiring NIV according to a Modified Wood Scale score of \u2265 4 points. Subjects were randomized to NIV management according to medical criteria (control group) or to protocolized management of NIV (protocol group). Hours of NIV, hospital stay, and supplemental oxygen use after discontinuation of NIV, severity changes after NIV initiation, respiratory symptoms, and proportion of intubations were considered as events of interest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      A total of 23 subjects were analyzed in the control group and 24 were analyzed in the protocol group. Hours of hospital stay, NIV, and supplemental oxygen post-NIV were not significantly different between groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .70, .69, and .68, respectively). There were also no differences in intubation rate (3 of 29 for the control group and 2 of 31 for the protocol group). For the total sample there was a statistically significant decrease in the Modified Wood Scale score after 1 h of NIV (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). A similar result was observed when performing a stratified intragroup analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>We observed that the implementation of an NIV management protocol that integrates initiation and discontinuation criteria for NIV is feasible. However, its use showed no advantages over a non-protocolized strategy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.05660","type":"journal-article","created":{"date-parts":[[2017,9,26]],"date-time":"2017-09-26T20:25:26Z","timestamp":1506457526000},"page":"1533-1539","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Impact of a Noninvasive Ventilation Protocol in Hospitalized Children With Acute Respiratory Failure"],"prefix":"10.1177","volume":"62","author":[{"given":"Yorschua","family":"Jalil","sequence":"first","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Damiani","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Faculty of Sciences, Pontificia Universidad Catolica de Valpara\u00edso, Valpara\u00edso, Chile."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Astudillo","sequence":"additional","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"},{"name":"School of Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Villarroel","sequence":"additional","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"},{"name":"adjunct instructors in kinesiology in UDA Health Sciences, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricio","family":"Bara\u00f1ao","sequence":"additional","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"},{"name":"adjunct instructors in kinesiology in UDA Health Sciences, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edson","family":"Bustos","sequence":"additional","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Silva","sequence":"additional","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mireya","family":"Mendez","sequence":"additional","affiliation":[{"name":"Hospital Josefina Martinez, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,9,26]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.4067\/S0370-41062011000300006"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2011.605"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000225089.21176.0B"},{"issue":"6","key":"e_1_3_1_5_2","doi-asserted-by":"crossref","first-page":"568","DOI":"10.4067\/S0370-41062006000600003","article-title":"Caracterizaci\u00f3n de la ventilaci\u00f3n mec\u00e1nica no invasiva pedi\u00e1trica hospitalaria","volume":"77","author":"Valenzuela VJ","year":"2006","unstructured":"Valenzuela VJ, , Donoso FA, , Le\u00f3n BJ, , Diaz RF, , Cruces RP. Caracterizaci\u00f3n de la ventilaci\u00f3n mec\u00e1nica no invasiva pedi\u00e1trica hospitalaria. Rev Chil Pediatr. 2006; 77(6):568\u2013576.","journal-title":"Rev Chil Pediatr"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2005"},{"key":"e_1_3_1_7_2","doi-asserted-by":"crossref","unstructured":"Ya\u00f1ez LJ Yunge M Emilfork M Lapadula M Alc\u00e1ntera A Fern\u00e1ndez C et al. A prospective randomized controlled trial of noninvasive ventilation in pediatric acute respiratory failure. 2008; 9(5):484\u2013489.","DOI":"10.1097\/PCC.0b013e318184989f"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22561"},{"key":"e_1_3_1_9_2","first-page":"45","article-title":"Asistencia ventilatoria no invasiva: Gu\u00eda para el manejo de pacientes con insuficiencia respiratoria aguda","volume":"3","author":"Paiva R","year":"2008","unstructured":"Paiva R, , Campos C, , Salinas P, , Prado F. Asistencia ventilatoria no invasiva: Gu\u00eda para el manejo de pacientes con insuficiencia respiratoria aguda. Neumol Pediatr. 2008; 3(supp1):45\u201353.","journal-title":"Neumol Pediatr"},{"issue":"3","key":"e_1_3_1_10_2","first-page":"399","article-title":"Ventila\u00e7\u00e3o n\u00e3o invasiva numa unidade de cuidados intensivos pedi\u00e1tricos","volume":"23","author":"Nunes P","year":"2010","unstructured":"Nunes P, , Abadesso C, , Almeida E, , Silvestre C, , Loureiro H, , Almeida H. Ventila\u00e7\u00e3o n\u00e3o invasiva numa unidade de cuidados intensivos pedi\u00e1tricos. 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