{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:13:35Z","timestamp":1788412415753,"version":"build-2803163510"},"reference-count":28,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T00:00:00Z","timestamp":1537833600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Bronchiectasis leads to reduced functional capacity, which might have implications for physical activity. The impact of dyspnea and long-term oxygen therapy on physical activity has never been investigated in subjects with bronchiectasis. Based on these findings, specific strategies could be applied to allow individuals to be more active in their daily life. In this study we aimed to evaluate physical activity, the impact of dyspnea and long-term oxygen therapy on physical activity, and the determinants of physical activity in subjects with bronchiectasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      We performed a cross-sectional study in 139 subjects with bronchiectasis (age 45 \u00b1 13 y, FVC 70 \u00b1 22% of predicted, FEV\n                      <jats:sub>1<\/jats:sub>\n                      54 \u00b1 25% of predicted) and 49 healthy subjects as controls. Physical activity was assessed using steps per day (measured with a pedometer), spirometry, incremental shuttle walking test (ISWT), and dyspnea.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Reduced physical activity was observed in subjects with bronchiectasis, who recorded a median (interquartile range) of 8,007 (5,131\u201310,432) steps\/d compared with controls, who recorded 10,994 (8,551\u201314,078) steps\/d (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Significant correlations were observed between physical activity and FVC (r = 0.43), FEV\n                      <jats:sub>1<\/jats:sub>\n                      (r = 0.36), ISWT (r = 0.37), and dyspnea (r = \u22120.48). Determinants for reduced physical activity included pulmonary function (R\n                      <jats:sup>2<\/jats:sup>\n                      = 0.150), dyspnea (R\n                      <jats:sup>2<\/jats:sup>\n                      = 0.075), ISWT (R\n                      <jats:sup>2<\/jats:sup>\n                      = 0.044), and long-term oxygen therapy (R\n                      <jats:sup>2<\/jats:sup>\n                      = 0.038); these factors explained 32% of the physical activity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Subjects with bronchiectasis exhibited reduced physical activity compared with healthy peers. Dyspnea has a negative impact on physical activity. Independent factors associated with physical activity included pulmonary function, dyspnea, functional capacity, and long-term oxygen therapy. These findings will guide strategies to enhance daily physical activity and to encourage subjects with bronchiectasis to be more active.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.05771","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T14:35:14Z","timestamp":1537886114000},"page":"1498-1505","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Reduced Physical Activity With Bronchiectasis"],"prefix":"10.1177","volume":"63","author":[{"given":"Anderson","family":"Jos\u00e9","sequence":"first","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamires Machado","family":"Ramos","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rejane Agnelo Silva","family":"de Castro","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiane Santos","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anderson Alves","family":"de Camargo","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Abensur","family":"Athanazio","sequence":"additional","affiliation":[{"name":"Pulmonary Division, Heart Institute, Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia Zahi","family":"Rached","sequence":"additional","affiliation":[{"name":"Pulmonary Division, Heart Institute, Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Stelmach","sequence":"additional","affiliation":[{"name":"Pulmonary Division, Heart Institute, Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Dal Corso","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,9,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra012519"},{"key":"e_1_3_3_3_2","first-page":"1","volume-title":"Strategies for the management of chronic bronchial sepsis: Proceedings of a symposium held at the Charing Cross Hospital","author":"Cole PJ","year":"1984","unstructured":"Cole PJ. A new look at the pathogenesis and management of persistent bronchial sepsis: a \u201cvicious cycle\u201d hypothesis and its logical therapeutic connotations. In Davies RJ. editor. Strategies for the management of chronic bronchial sepsis: Proceedings of a symposium held at the Charing Cross Hospital. London: Medical Education Services. 1984; 12:1\u201320."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.060913"},{"key":"e_1_3_3_5_2","first-page":"32","article-title":"Assessment and investigation of adults with bronchiectasis","volume":"52","author":"Drain M","year":"2011","unstructured":"Drain M, , Elborn SJ. Assessment and investigation of adults with bronchiectasis. Eur Respir Mon, 2011; 52:32\u201343.","journal-title":"Eur Respir Mon"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.10551686"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2013.11.019"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-015-0046-7"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.04154"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2008.09.019"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00046814"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008483-200505000-00011"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132010000400006"},{"key":"e_1_3_3_14_2","first-page":"iii1","article-title":"Diretrizes para testes de fun\u00e7\u00e3o pulmonar","volume":"28","author":"Sociedade Brasileira de Pneumologia e Tisiologia","year":"2002","unstructured":"Sociedade Brasileira de Pneumologia e Tisiologia. Diretrizes para testes de fun\u00e7\u00e3o pulmonar. J Pneumol, 2002; 28(Suppl 3):iii1\u2013iii82.","journal-title":"J Pneumol"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132007000400008"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.47.12.1019"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-198205000-00012"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2011.07.023"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132008001200005"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000126777.50188.73"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.10.3.437"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e31817c7133"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00301103"},{"issue":"25","key":"e_1_3_3_24_2","first-page":"27","article-title":"Pathophysiological basis of exercise training in patients with chronic obstructive lung disease","volume":"5","author":"Pr\u00e9faut C","year":"1995","unstructured":"Pr\u00e9faut C, , Varray A, , Vallet G. Pathophysiological basis of exercise training in patients with chronic obstructive lung disease. Eur Respir Rev, 1995; 5(25):27\u201332.","journal-title":"Eur Respir Rev"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.123.1.136"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1080\/15412555.2016.1260538"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2015.1067294"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-2521"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2014"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.05771","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.05771","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.05771","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:26:59Z","timestamp":1775467619000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.05771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,25]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.4187\/respcare.05771"],"URL":"https:\/\/doi.org\/10.4187\/respcare.05771","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9,25]]}}}