{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:24:57Z","timestamp":1785414297338,"version":"3.56.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>\n                      The balance of oxygen delivery and consumption is essential in patients who are critically ill. Mixed venous oxygen saturation (S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      ) is a standard method to evaluate oxygen delivery and consumption during anesthesia. However, S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      is monitored through a pulmonary artery catheter, which is invasive. Regional cerebral oxygenation (rScO\n                      <jats:sub>2<\/jats:sub>\n                      ) reflects oxygen saturation in a small region of the frontal lobes and is monitored noninvasively through near-infrared spectroscopy. In the present study, the correlation between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      was calculated during off-pump coronary artery bypass grafting surgery to determine whether a positive correlation exists between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      A total of 56 subjects were consecutively enrolled in the study. Then rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      were simultaneously monitored. The parameters were recorded at 5 time points: T\n                      <jats:sub>1<\/jats:sub>\n                      , 10 min after intubation (1.0 F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      for 10 min); T\n                      <jats:sub>2<\/jats:sub>\n                      , 20 min after intubation (0.60 F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      for 10 min); T\n                      <jats:sub>3<\/jats:sub>\n                      , at the end of the revascularization of the left anterior descending artery (0.60 F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      ); T\n                      <jats:sub>4<\/jats:sub>\n                      , after protamine infusion (0.60 F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      ); and T\n                      <jats:sub>5<\/jats:sub>\n                      , 10 min after protamine infusion (1.0 F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      for 10 min). The correlation between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      and the variation trend between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      when F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      increased from 0.60 to 1.0 were analyzed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      There was a significant positive correlation between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      at these 5 time points (r\n                      <jats:italic toggle=\"yes\">\n                        <jats:sup>2<\/jats:sup>\n                      <\/jats:italic>\n                      = 0.77, 0.81, 0.70, 0.83, and 0.92, respectively). There also was a significant positive correlation between \u0394 rScO\n                      <jats:sub>2<\/jats:sub>\n                      and \u0394 S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 112, r\n                      <jats:italic toggle=\"yes\">\n                        <jats:sup>2<\/jats:sup>\n                      <\/jats:italic>\n                      = 0.72,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Linear regression analysis revealed that S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      had a positive correlation with rScO\n                      <jats:sub>2<\/jats:sub>\n                      and cardiac output (r\n                      <jats:italic toggle=\"yes\">\n                        <jats:sup>2<\/jats:sup>\n                      <\/jats:italic>\n                      = 0.68,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .013).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>\n                      There was a positive correlation between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      during off-pump coronary artery bypass grafting surgery, and there also was a positive correlation in the variation trend between rScO\n                      <jats:sub>2<\/jats:sub>\n                      and S\n                      <jats:sub>\n                        v\u0304O\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.05772","type":"journal-article","created":{"date-parts":[[2018,5,29]],"date-time":"2018-05-29T12:55:12Z","timestamp":1527598512000},"page":"988-993","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Positive Correlation Between Regional Cerebral Oxygen Saturation and Mixed Venous Oxygen Saturation During Off-Pump Coronary Artery Bypass Surgery"],"prefix":"10.1177","volume":"63","author":[{"given":"Zheng","family":"Guan","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing-Jie","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology, the Second Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Feng","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, the First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,8,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jopan.2005.09.006"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200310000-00036"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-013-9507-9"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10877-012-9348-y"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2015.03.008"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2009.206367"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3171\/2013.12.JNS131089"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000180205.85490.85"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12122"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.08.070"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000246814.29362.f4"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2006.09.010"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2001.113167"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.05.047"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.4.423"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1159\/000101063"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.12.021"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivr102"},{"issue":"10","key":"e_1_3_2_20_2","first-page":"952","article-title":"Relationship 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