{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:31:33Z","timestamp":1787031093274,"version":"build-2736575974"},"reference-count":38,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Bronchiectasis is characterized by abnormal and permanent dilatation of the bronchi, caused mainly by the progression of inflammatory processes and loss of the ability to remove mucus. Techniques to clear the airways are essential for the treatment of these patients. In this study, we aimed to evaluate the acute effects of oscillatory PEP and thoracic compression on both the clearance of secretions and impedance of airways in subjects with bronchiectasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>This was a randomized crossover single-blinded study that involved both subjects with bronchiectasis and healthy subjects evaluated by using an impulse oscillometry system, which assessed resistance at 5 Hz and resistance 20 Hz, reactance at 5 Hz, reactance area, and resonant frequency, before, after, and 30 min after oscillatory PEP, chest compression, or control sessions. Dry and total weights, adhesiveness, purulence of the expectorated secretions, the dyspnea scale score, the acceptability and tolerance scale score, pulse oximetry, and difficulty in expectoration were also assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The dry and total weights of secretions were higher after the use of the oscillatory PEP technique than those in a control session (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .005 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .039, respectively). In the bronchiectasis group, there was a decrease after oscillatory PEP in total airway resistance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .04), peripheral resistance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .005), and reactance area (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .001). After compression, there was a decrease in peripheral resistance Hz (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .001) and reactance area (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .001). In the healthy group, there was an increase in resistance at 5 Hz (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .02) after oscillatory PEP. There were no differences in acceptability and tolerance, dyspnea, and oxygen saturation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The oscillatory PEP technique was effective for the removal of secretions and in decreasing total and peripheral respiratory system resistance; thoracic compression had comparable positive effects on the peripheral resistance. Both techniques were safe and well tolerated by the subjects with bronchiectasis. ClinicalTrials.gov registration NCT02509637.)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.06025","type":"journal-article","created":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T13:29:10Z","timestamp":1559050150000},"page":"818-827","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Acute Effects of Oscillatory PEP and Thoracic Compression on Secretion Removal and Impedance of the Respiratory System in Non\u2013Cystic Fibrosis Bronchiectasis"],"prefix":"10.1177","volume":"64","author":[{"given":"Let\u00edcia Helena","family":"de Souza Simoni","sequence":"first","affiliation":[{"name":"Department of Health Science, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele Oliveira","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Department of Health Science, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo Celso Dutra","family":"de Souza","sequence":"additional","affiliation":[{"name":"Department of Health Science, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Baddini-Martinez","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel Koenigkam","family":"Santos","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada Clarice","family":"Gastaldi","sequence":"additional","affiliation":[{"name":"Department of Health Science, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,7,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.6.1430"},{"issue":"5","key":"e_1_3_3_3_2","first-page":"259","article-title":"Bronchiectasis: diagnostic and therapeutic features","volume":"29","author":"Moreira JS","year":"2003","unstructured":"Moreira JS, , Porto NS, , Peixoto JJ, , Felicetti JC, , Cardoso PFG, , Moreira ALS, , Andrade CF. 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