{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T21:36:29Z","timestamp":1775511389574,"version":"3.50.1"},"reference-count":29,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T00:00:00Z","timestamp":1556582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>\n                      High-flow nasal cannula (HFNC) oxygen therapy is used to deliver an F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      from 0.21 to 1.0. The double-trunk mask (DTM) is a device designed to increase the F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      in patients with a high inspiratory flow demand. The aim of our study was to evaluate the effect of DTM in hypoxemic subjects already receiving HFNC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We report a prospective multi-center crossover pilot study including 15 subjects treated with HFNC for acute hypoxemic respiratory failure. Measurements were performed at the end of 30-min periods with HFNC only, with HFNC + DTM, and again with HFNC only.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Compared with HFNC alone, HFNC + DTM increased P\n                      <jats:sub>\n                        aO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      from 68 \u00b1 14 mm Hg to 85 \u00b1 22 mm Hg (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) and did not affect P\n                      <jats:sub>\n                        aCO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .18). In the 11 responders, the P\n                      <jats:sub>\n                        aO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      increased from 63 \u00b1 12 mm Hg to 88 \u00b1 23 mm Hg (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). No complications were reported during DTM use.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>\n                      In subjects receiving oxygen via HFNC, the addition of the DTM over the HFNC increased P\n                      <jats:sub>\n                        aO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      without changing the P\n                      <jats:sub>\n                        aCO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.06520","type":"journal-article","created":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T15:46:12Z","timestamp":1556639172000},"page":"908-914","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["The Double-Trunk Mask Improves Oxygenation During High-Flow Nasal Cannula Therapy for Acute Hypoxemic Respiratory Failure"],"prefix":"10.1177","volume":"64","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Duprez","sequence":"first","affiliation":[{"name":"ICU, Epicura Hospital, Hornu, Belgium, the Institut de Recherche Exp\u00e9rimentale et Clinique (IREC), Pole de Pneumologie, ORL &amp; Dermatologie, Service de Pneumologie, Universit\u00e9 Catholique de Louvain, Brussels, Belgium, and the Laboratoire de l'Effort et du Mouvement Condorcet, Tournai, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Bruyneel","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Universit\u00e9 Catholique de Louvain, Brussels, Belgium, and the Haute Ecole Provinciale Condorcet, Mons, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahram","family":"Machayekhi","sequence":"additional","affiliation":[{"name":"ICU, Epicura Hospital, Hornu, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Droguet","sequence":"additional","affiliation":[{"name":"ICU, Tivoli Hospital, La Louvi\u00e8re, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Bouckaert","sequence":"additional","affiliation":[{"name":"ICU, Tivoli Hospital, La Louvi\u00e8re, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serge","family":"Brimioulle","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Erasme Hospital, Brussels, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Cuvelier","sequence":"additional","affiliation":[{"name":"Laboratoire de l'Effort et du Mouvement Condorcet, Tournai, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Reychler","sequence":"additional","affiliation":[{"name":"Institut de Recherche Exp\u00e9rimentale et Clinique (IREC), Pole de Pneumologie, ORL &amp; Dermatologie, Service de Pneumologie, Universit\u00e9 Catholique de Louvain, Brussels, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,30]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.04577"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4277-8"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.47.8.609"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.05500604"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.04963"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.10550453"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X1103900620"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2007.05026.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201707-548FR"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(00)00154-7"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1049023X00035317"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199806000-00022"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc1072"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0761-8425(07)72857-7"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503326"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.01106"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02358"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.01941"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0736-4679(93)90627-J"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/139.3.627"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1929.02710200034009"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1970.tb00192.x"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197601000-00019"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198007000-00010"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12268"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/002013240004500108"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.100.6.1582"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.3.787"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02851"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.06520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.06520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.06520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T11:09:07Z","timestamp":1775473747000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.06520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,30]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.4187\/respcare.06520"],"URL":"https:\/\/doi.org\/10.4187\/respcare.06520","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4,30]]}}}