{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T11:19:50Z","timestamp":1775474390323,"version":"3.50.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Adaptive servoventilation (ASV) is a recently developed ventilation mode designed to stabilize ventilation in patients with central sleep apnea and Cheyne-Stokes respiration. Alternatively, modes aiming to maintain average ventilation over several breaths, such as average volume-assured pressure support (AVAPS) and intelligent volume-assured pressure support (iVAPS), could be efficient during ventilation instability by reducing central events. These modes are available on a variety of devices. This bench evaluation studied the response of these different modes and devices to simulated transient hypoventilation events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      Three home ventilation devices operating in ASV modes (AirCurve 10 CS Pacewave, ResMed; DreamStation autoSV, Philips; Prisma CR, L\u00f6wenstein) and 2 ventilators with the AVAPS mode (DreamStation BiPAP, Philips; Lumis 150 iVAPS, ResMed) were evaluated during transient central hypopnea\/hypoventilation simulations characterized by a constant breathing frequency of 15 breaths\/min and a progressive decrease of tidal volume (V\n                      <jats:sub>T<\/jats:sub>\n                      ) from 500 mL to 50 mL, in 18, 12, 9, and 6 breaths, respectively, followed by a progressive return to the baseline at the same rate.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The AirCurve 10 CS Pacewave reacted to a V\n                      <jats:sub>T<\/jats:sub>\n                      decrease between 80% and 50% of baseline V\n                      <jats:sub>T<\/jats:sub>\n                      . DreamStation BiPAP and Prisma CR reacted when V\n                      <jats:sub>T<\/jats:sub>\n                      decreased to between 60% and 30% of baseline V\n                      <jats:sub>T<\/jats:sub>\n                      , whereas the AVAPS response to hypopnea occurred during the crescendo phase of hypopnea\/hypoventilation V\n                      <jats:sub>T<\/jats:sub>\n                      . The iVAPS response was between that of the AirCurve 10 CS Pacewave and the other ASV devices. Among the ASV devices, the minimum V\n                      <jats:sub>T<\/jats:sub>\n                      was higher with AirCurve 10 CS Pacewave, followed by the Prisma CR and the DreamStation BiPAP. Minimum V\n                      <jats:sub>T<\/jats:sub>\n                      was not influenced by AVAPS and was improved by iVAPS without outperforming the AirCurve 10 CS Pacewave. Maximum V\n                      <jats:sub>T<\/jats:sub>\n                      was increased by iVAPS, whereas ASV devices did not induce a significant V\n                      <jats:sub>T<\/jats:sub>\n                      overshoot.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>ASV devices improved central hypopnea\/hypoventilation events without inducing hyperpnea events and therefore were better adapted than AVAPS and iVAPS devices, with notable differences in their responses to hypoventilation events.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.07213","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T17:15:46Z","timestamp":1594746946000},"page":"1258-1267","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Response of Home-Use Adaptive Pressure Modes to Simulated Transient Hypoventilation"],"prefix":"10.1177","volume":"65","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Lofaso","sequence":"first","affiliation":[{"name":"Department of Clinical Physiology, AP-HP H\u00f4pital Raymond Poincar\u00e9, Universit\u00e9 de Versailles Saint Quentin en Yvelines, Garches, France."},{"name":"ERPHAN Research Unit, Universit\u00e9 de Versailles-Saint-Quentin-en-Yvelines, Garches, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Leroux","sequence":"additional","affiliation":[{"name":"ASV Sant\u00e9, Paris, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghilas","family":"Boussaid","sequence":"additional","affiliation":[{"name":"ERPHAN Research Unit, Universit\u00e9 de Versailles-Saint-Quentin-en-Yvelines, Garches, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9l\u00e8ne","family":"Prigent","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology, AP-HP H\u00f4pital Raymond Poincar\u00e9, Universit\u00e9 de Versailles Saint Quentin en Yvelines, Garches, France."},{"name":"INSERM 1179, Universit\u00e9 de Versailles-Saint-Quentin-en-Yvelines, Garches, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Louis","sequence":"additional","affiliation":[{"name":"INSERM U955, Cr\u00e9teil, France."},{"name":"ERL 7000, CNRS, Cr\u00e9teil, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/30.4.468"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.3.815"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.4.9908114"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.1438"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-012-0188-3"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2982"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0879-5"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181cb0d7b"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00144807"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.2.343"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200209-999OC"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.072371"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1992.73.6.2462"},{"issue":"3","key":"e_1_3_2_15_2","first-page":"236","article-title":"Sleep-induced breathing instability. 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