{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T13:16:58Z","timestamp":1788959818080,"version":"build-2803163510"},"reference-count":30,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T00:00:00Z","timestamp":1581984000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>We tested whether work of breathing in premature newborns estimated by phase angle (\u03b8) by using respiratory inductance plethysmography is decreased during neurally-adjusted ventilatory assist (NAVA) noninvasive ventilation (NIV) versus NIV alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>NAVA NIV and NIV were applied in random order while using respiratory inductance plethysmography to measure the phase angle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>Patient-ventilator asynchrony was decreased during NAVA NIV; however, the phase angle was not different between the modes. A large number of repeated assists with switches to backup were found when using NAVA NIV. Results of the analysis indicated these were due to the apnea alarm limit set during NAVA NIV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The improvement in patient-ventilator synchrony supports the hypothesis that work of breathing may be decreased with NAVA NIV; however, we were unable to demonstrate this with our study design. Short apnea time settings with NAVA NIV led to a large number of switches to backup and repeated assists during the same neural effort. (ClinicalTrials.gov registration NCT02788110.)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.07257","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T13:34:37Z","timestamp":1582032877000},"page":"946-953","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Work of Breathing in Premature Neonates: Noninvasive Neurally-Adjusted Ventilatory Assist versus Noninvasive Ventilation"],"prefix":"10.1177","volume":"65","author":[{"given":"David N","family":"Matlock","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Neonatology Division, University of Arkansas for Medical Sciences, Little Rock, Arkansas."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shasha","family":"Bai","sequence":"additional","affiliation":[{"name":"Center for Biostatistics, Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D","family":"Weisner","sequence":"additional","affiliation":[{"name":"Equilibrated Bio Systems, Smithtown, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norman","family":"Comtois","sequence":"additional","affiliation":[{"name":"Keenan Research Centre for Biomedical Science, St. Michael\u2019s Hospital, Toronto, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Beck","sequence":"additional","affiliation":[{"name":"Keenan Research Centre for Biomedical Science, St. Michael\u2019s Hospital, Toronto, Ontario, Canada."},{"name":"Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada."},{"name":"Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada."},{"name":"Institute for Biomedical Engineering and Science Technology, Ryerson University and St. Michael\u2019s Hospital, Toronto, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christer","family":"Sinderby","sequence":"additional","affiliation":[{"name":"Keenan Research Centre for Biomedical Science, St. Michael\u2019s Hospital, Toronto, Ontario, Canada."},{"name":"Department of Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada."},{"name":"Institute for Biomedical Engineering and Science Technology, Ryerson University and St. Michael\u2019s Hospital, Toronto, Ontario, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry E","family":"Courtney","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Neonatology Division, University of Arkansas for Medical Sciences, Little Rock, Arkansas."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,2,18]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2007.11.004"},{"issue":"8","key":"e_1_3_2_3_2","first-page":"1045","article-title":"Noninvasive positive pressure ventilation or conventional mechanical ventilation for neonatal continuous positive airway pressure failure","volume":"5","author":"Badiee Z","year":"2014","unstructured":"Badiee Z, , Nekooie B, , Mohammadizadeh M. 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