{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T02:42:09Z","timestamp":1788748929301,"version":"build-2803163510"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Lung ultrasound (LUS) is an effective imaging modality that can differentiate pathological lung from non-diseased lung. We aimed to explore the value of bedside LUS in patients with severe and critical coronavirus disease 2019 (COVID-19)-associated lung injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>Sixty-three severe and 33 critical hospitalized subjects with COVID-19 were enrolled in this study. Bedside LUS was performed in all subjects; chest computed tomography was performed on the same day as bedside LUS in 23 cases. The LUS protocol consisted of 12 scanning zones. LUS score based on B-lines and lung consolidation was evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The most common abnormality of LUS was the various forms of B-lines, detected in 93 (96.9%) subjects; as the second most frequent abnormality, 80 (83.3%) subjects exhibited lung consolidation, mainly located in the posterior lung region. Twenty-four (25.0%) subjects had pleural line abnormalities, and 16 (16.7%) had pleural effusion; 78 (81.3%) subjects had \u2265 2 abnormal LUS patterns, and 93 (96.9%) had bilateral lung involvement. The proportion of bilateral or unilateral lung consolidation and pleural effusion in the critical COVID-19 group were higher than that in the severe group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05). The lung consolidation of critical subjects showed a marked increase in most lung areas, including bilateral lateral lung, posterior lung, and left anterior-inferior lung area. The median (interquartile range) LUS scores of critical cases were higher than those of severe cases: left: 14 (12\u201317) vs 7 (5\u201312); right: 14 (10\u201316) vs 8 (3\u201312); bilateral: 28 (23\u201331) vs 15 (8\u201322) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001 for all). There was a good correlation between the LUS score and the chest computed tomography score (r = 0.887,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The most common abnormal LUS pattern in subjects with severe and critical COVID-19 pneumonia was B-lines, followed by lung consolidation. Bedside LUS can provide important information for pulmonary involvement in patients with COVID-19.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.08382","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T15:00:31Z","timestamp":1616511631000},"page":"920-927","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Value of Bedside Lung Ultrasound in Severe and Critical COVID-19 Pneumonia"],"prefix":"10.1177","volume":"66","author":[{"given":"Shuangshuang","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuman","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqin","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxing","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."},{"name":"Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,3,23]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/v12020135"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1585"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1750307"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-020-04735-9"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30566-3"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1757-7241-20-18"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-019-00309-1"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000260674.60761.85"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2513-4"},{"key":"e_1_3_2_13_2","unstructured":"National 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