{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T08:28:11Z","timestamp":1782808091708,"version":"3.54.5"},"reference-count":39,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Because impulse oscillometry (IOS) can detect changes in the small airways and is safer to perform during the COVID-19 pandemic than other pulmonary function tests, it may have value in investigating pulmonary sequelae in COVID-19 survivors. This study evaluated the performance of IOS in detecting lung abnormalities in COVID-19 survivors and investigated the associations of the findings with those of lung ultrasound (LUS) and spirometry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>In this cross-sectional study, 117 subjects underwent IOS at a frequency range of 4\u201320 Hz 2 months after COVID-19 diagnosis. They also underwent spirometry and LUS, and their aeration scores were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      On IOS, the resonance frequency was &gt; 12 Hz, and the area under the reactance curve was &gt; 3.60 cm H\n                      <jats:sub>2<\/jats:sub>\n                      O\/L\/s in 70 (59.8%) and 55 (47.0%) subjects, respectively. A heterogeneity of resistance between R4 and R20 (R4-R20) &gt; 20% was observed in 60 (51.3%) participants. Based on their abnormalities in resistive and reactive parameters, 76 (65.0%) participants had abnormal IOS. Spirometry abnormalities were detected in 40 (34.2%) cases. LUS was abnormal in 51 (43.6%) participants, and the median aeration score was 0 (0\u20138) points. Abnormal IOS was associated with abnormal LUS\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      &lt; .001) and abnormal spirometry\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      = .002). Abnormal spirometry had a significant but weaker association with abnormal LUS\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      = .031). In participants who reported hospitalization, abnormal IOS was associated with both abnormal LUS\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      = .001) and abnormal spirometry\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      = .006). In participants who did not report hospitalization, abnormal IOS was associated with abnormal LUS\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      &lt; .001) but not abnormal spirometry\n                      <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                      = .063).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>In COVID-19 survivors, IOS detected changes even when spirometry was normal. In these individuals, IOS parameters were more strongly associated with abnormalities on LUS than with abnormalities on spirometry.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.09193","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T12:45:13Z","timestamp":1631018713000},"page":"1691-1698","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Impulse Oscillometry Findings and Their Associations With Lung Ultrasound Signs in COVID-19 Survivors"],"prefix":"10.1177","volume":"66","author":[{"given":"Agnaldo J","family":"Lopes","sequence":"first","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil."},{"name":"Rehabilitation Sciences Postgraduation Program, Augusto Motta University Center, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago T","family":"Mafort","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana S","family":"da Cal","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura B","family":"Monnerat","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia F","family":"Litrento","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Ramos","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael F J","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia H","family":"da Costa","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rog\u00e9rio","family":"Rufino","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, State University of Rio de Janeiro, Rio de Janeiro, Brazil."},{"name":"Postgraduate Program in Medical Sciences, School of Medical Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,7]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3001"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01217-2020"},{"key":"e_1_3_2_4_2","article-title":"Residual lung injury in patients recovering from COVID-19 critical illness: a prospective longitudinal point-of-care lung ultrasound study","author":"Alharthy A","year":"2020","unstructured":"Alharthy A, , Abuhamdah M, , Balhamar A, et al. 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