{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:49:07Z","timestamp":1775472547161,"version":"3.50.1"},"reference-count":37,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Clinical diagnosis of ICU-acquired pneumonia after cardiothoracic surgery is challenging. Johanson criteria (chest radiograph infiltrate, purulent tracheal secretions, fever, and leukocytosis) fail in half the cases. A high Clinical Pulmonary Infection Score (CPIS) and \u2265 2-point increase in Sequential Organ Failure Assessment (SOFA) score (SOFA\u2191 \u2265 2) may improve diagnosis. The aim of the study was to evaluate whether CPIS or SOFA\u2191 \u2265 2 contributes to predict ICU-acquired pneumonia in subjects after cardiothoracic surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We used a prospective observational design. Spiegelhalter-Knill-Jones scoring systems including CPIS or SOFA\u2191 \u2265 2, together with other clinical and laboratory variables, were developed in a derivation cohort. A positive quantitative pulmonary sample culture was required to confirm ICU-acquired pneumonia. Area under the receiver operating characteristic curve (AUROC) was computed for each of the 2 scoring systems. The best system was evaluated in a validation cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Derivation and validation cohorts included 172 and 108 subjects, with 410 and 216 suspected ICU-acquired pneumonia episodes, respectively. AUROC was 0.53 \u00b1 0.03 for CPIS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .29) and 0.54 \u00b1 0.03 for SOFA\u2191 \u2265 2 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .29). Adding purulent tracheal secretions and leukocytosis to SOFA\u2191 \u2265 2 (SOFA model) increased AUROC to 0.65 \u00b1 0.03 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). Adding catecholamine use to CPIS (CPIS model) increased AUROC only slightly, to 0.57 \u00b1 0.03. The probabilities predicted by the SOFA model were reliable, especially when high or low.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>A clinical scoring system including at least SOFA\u2191 \u2265 2 increase barely improved ICU-acquired pneumonia prediction in subjects after cardiothoracic surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.09911","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T07:45:19Z","timestamp":1663055119000},"page":"1558-1567","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Including Organ Dysfunctions in a Predictive Score for Nosocomial Pneumonia After Cardiothoracic Surgery"],"prefix":"10.1177","volume":"67","author":[{"given":"Talna","family":"Kortchinsky","sequence":"first","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thibaut","family":"Genty","sequence":"additional","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Gigandon","sequence":"additional","affiliation":[{"name":"Bacteriology Laboratory, Marie Lannelongue Hospital, Le Plessis Robinson, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Calypso","family":"Roman","sequence":"additional","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saida","family":"R\u00e9zaiguia-Delclaux","sequence":"additional","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, France."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"St\u00e9phan","sequence":"additional","affiliation":[{"name":"Cardiothoracic Intensive Care Unit, Marie Lannelongue Hospital, Le Plessis Robinson, France; and Paris Saclay University, School of Medicine, Le Kremlin Bic\u00eatre, France."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,9,13]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.12.055"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.2717"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201001-0094OC"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.04059"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.2.547"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.4_suppl_2.191S"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/143.5_Pt_1.1121"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200212-1449OC"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2008.01.006"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-020-00721-4"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-003-2018-2"},{"issue":"21","key":"e_1_3_3_13_2","first-page":"2063","article-title":"Severe sepsis and septic shock","volume":"369","author":"Angus DC","year":"2013","unstructured":"Angus DC, , van der Poll T. Severe sepsis and septic shock. N Engl J Med, 2013; 369(21):2063.","journal-title":"N Engl J Med"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-05980-0"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0287"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw504"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn162"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2017.11.006"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00582-2017"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-132-8-200004180-00004"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06260-7"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMclde1809210"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-35717"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000249826.81273.E4"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-77-5-701"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.2.9909095"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.21.2703"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06036-z"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.143.1.7063747"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.2307\/2981737"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-5089(21)00720-3"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2929"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.14.1583"},{"issue":"9","key":"e_1_3_3_34_2","first-page":"805-809","article-title":"The chest radiograph in critically ill surgical patients is inaccurate in predicting ventilator-associated pneumonia","volume":"65","author":"Butler KL","year":"1999","unstructured":"Butler KL, , Sinclair KE, , Henderson VJ, , McKinney G, , Mesidor DA, , Katon-Benitez I. The chest radiograph in critically ill surgical patients is inaccurate in predicting ventilator-associated pneumonia. 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