{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:27:05Z","timestamp":1784672825070,"version":"3.55.0"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Mechanical insufflation-exsufflation (MI-E) devices are used to improve airway clearance in individuals with acute respiratory failure. Some MI-E devices measure cough peak flow (CPF) during MI-E to optimize pressure adjustments. The aim was to compare CPF and effective cough volume (ECV: volume expired\/coughed &gt; 3 L\/s) measurements between 4 MI-E devices under simulated conditions of stable versus collapsed airway.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>\n                      Four MI-E devices were tested on the bench. Each device was connected via a standard circuit to a collapsible tube placed in an airtight chamber that was attached to a lung model with adjustable compliance and resistance. Pressure was measured upstream and downstream the collapsing tube; air flow was measured between the chamber and the lung model. Each device was tested in 2 conditions: collapse condition (0 cm H\n                      <jats:sub>2<\/jats:sub>\n                      O) and no-collapse condition (\u221270 cm H\n                      <jats:sub>2<\/jats:sub>\n                      O). For each condition, 6 combinations of inspiratory\/expiratory pressures were applied. CPF was measured at the \u201cmouth level\u201d by the device built-in flow meter and at the \u201ctracheal level\u201d by a dedicated pneumotachograph. Comparisons were performed with non-parametric tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      CPF values measured at the tracheal level and ECV values differed between devices for each inspiratory\/expiratory pressure in the collapse and no-collapse conditions (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). CPF values were significantly lower at the tracheal level in the collapse as compared with the no-collapse condition (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001 for each device), whereas they were higher at the mouth level (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05) for 3 of the 4 devices.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>CPF values differed significantly across MI-E devices, highlighting limitation(s) of using only CPF values to determine cough effectiveness. In simulated of airway collapse, CPF increased at the mouth, whereas it decreased at the tracheal level.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.10086","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T22:55:15Z","timestamp":1679698515000},"page":"462-469","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of Four Mechanical Insufflation-Exsufflation Devices: Effect of Simulated Airway Collapse on Cough Peak Flow"],"prefix":"10.1177","volume":"68","author":[{"given":"Nicolas","family":"Terzi","sequence":"first","affiliation":[{"name":"Centre Hospitalier Universitaire Grenoble Alpes, M\u00e9decine Intensive R\u00e9animation, INSERM, Universit\u00e9 Grenoble-Alpes, Grenoble, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Vaugier","sequence":"additional","affiliation":[{"name":"Clinical Investigation Centre 1429, APHP, H\u00f4pital Raymond-Poincar\u00e9, Garches, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Gu\u00e9rin","sequence":"additional","affiliation":[{"name":"Medecine Intensive-R\u00e9animation, Groupement Hospitalier Centre, H\u00f4pital Edouard Herriot, Hospices Civils de Lyon, Lyon, France; Universit\u00e9 de Lyon, Lyon, France; and Institut Mondor de Recherches Biom\u00e9dicales, INSERM 955 CNRS ERL 7000, Cr\u00e9teil, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Prigent","sequence":"additional","affiliation":[{"name":"INSERM U1179, END-ICAP, Universit\u00e9 de Versailles-Saint Quentin, University of Paris-Saclay, Montigny-le-Bretonneux, France; and Service de Physiologie et Explorations Fonctionnelles, GH Paris Ile de France Ouest-Site Raymond Poincar\u00e9-AP-HP, Garches, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghilas","family":"Boussaid","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, ERPHAN, Versailles, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Leroux","sequence":"additional","affiliation":[{"name":"ASV Sant\u00e9, 125, Avenue Louis Roche, Gennevilliers, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Delorme","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, UVSQ, ERPHAN, Versailles, France; Universit\u00e9 de Lyon, Lyon, France; and Institut Mondor de Recherches Biom\u00e9dicales, INSERM 955 CNRS ERL 7000, Cr\u00e9teil, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Lofaso","sequence":"additional","affiliation":[{"name":"Service de Physiologie et Explorations Fonctionnelles, GH Paris Ile de France Ouest-Site Raymond Poincar\u00e9-AP-HP, Garches, France; and Universit\u00e9 Paris-Saclay, UVSQ, ERPHAN, Versailles, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Louis","sequence":"additional","affiliation":[{"name":"Institut Mondor de Recherches Biom\u00e9dicales, INSERM 955 CNRS ERL 7000, Cr\u00e9teil, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,4,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.07521296"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.04877"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-207555"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00048102"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00853.2013"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.4.2159"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.012716"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbr.2018.10.012"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.06478"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.4.1400"},{"issue":"1","key":"e_1_3_2_12_2","first-page":"39","article-title":"Peak cough flow measurement with a pneumotachograph and a portable peak flow meter in patients with neuromuscular diseases","volume":"23","author":"Rodrigues PR","year":"2017","unstructured":"Rodrigues PR, , Brito PU, , Fernandes L, , Rodrigues C, , Reis A, , Moita J. Peak cough flow measurement with a pneumotachograph and a portable peak flow meter in patients with neuromuscular diseases. Rev Port Pneumol (2006), 2017; 23(1):39-40.","journal-title":"Rev Port Pneumol (2006)"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.06124"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/36\/2\/243"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.07454"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.03809"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2019.06.012"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201406-264OC"}],"container-title":["Respiratory Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.4187\/respcare.10086","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.10086","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4187\/respcare.10086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T08:57:50Z","timestamp":1775465870000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4187\/respcare.10086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.4187\/respcare.10086"],"URL":"https:\/\/doi.org\/10.4187\/respcare.10086","relation":{},"ISSN":["0020-1324"],"issn-type":[{"value":"0020-1324","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]}}}