{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:58:07Z","timestamp":1775469487334,"version":"3.50.1"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>\n                      Adaptive ventilation mode (AVM) is a automated mode of mechanical ventilation. AVM is comprable to adaptive support ventilation (ASV). Both recommend a tidal volume (V\n                      <jats:sub>T<\/jats:sub>\n                      ) and breathing frequency (f) combination based on lung mechanics, but AVM also automatically adjusts rise time and flow termination of pressure support breaths. How these added features of AVM affect V\n                      <jats:sub>T<\/jats:sub>\n                      and f recommendations compared to ASV is not clear. The present study compared these 2 modes in a test lung with obstructive and restrictive mechanics.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>The experiment was performed in a simulated lung model in which the compliance (C) and resistance (R) could be altered independently. The ventilatory parameters at different minute volumes (MinVol%) in AVM or ASV mode were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      When MinVol% was set at 100%, AVM provided a similar V\n                      <jats:sub>T<\/jats:sub>\n                      and f combination compared to ASV with decreasing compliance or increasing resistance. However, when MinVol% was increased to 250% simulating hyperventilation, for the severely obstructive lung (C60, R70) model, AVM provided a significantly higher f (26 \u00b1 0.6 breaths\/min vs 7.00 \u00b1 0 breaths\/min in ASV) and lower V\n                      <jats:sub>T<\/jats:sub>\n                      (240 \u00b1 80 mL vs 491 \u00b1 131 mL in ASV).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>\n                      The addition of automatic control of rise time and flow termination functions did not affect recommended ventilator settings in AVM in the noncompliant or obstructive lung when minute ventilation (V\u0307\n                      <jats:sub>E<\/jats:sub>\n                      ) was low. At higher V\u0307\n                      <jats:sub>E<\/jats:sub>\n                      , AVM compared to ASV recommended a ventilatory strategy with lower V\n                      <jats:sub>T<\/jats:sub>\n                      and higher f. These results need to be validated in patients.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.10475","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T13:41:33Z","timestamp":1680615693000},"page":"669-675","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Effects of Automatic Inspiratory Rise Time and Flow Termination on Operation of Closed-Loop Ventilation"],"prefix":"10.1177","volume":"68","author":[{"given":"Shih Hsing","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Respiratory Therapy, Fu Jen Catholic University, New Taipei City, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin Pyng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Chest Medicine, Taiwan Landseed Hospital, Tao Yuan County, Taiwan and National Defense Medical Center, Taipei City, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuh Chin T","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung Kan","family":"Peng","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Tri-Service General Hospital, Taipei City, Taiwan; and National Defense Medical Center, Taipei City, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1750-x"},{"key":"e_1_3_2_3_2","article-title":"COVID-19 pandemic and mechanical ventilation: facing the present, designing the future","author":"Holanda MA","year":"2020","unstructured":"Holanda MA, , Pinheiro BV. COVID-19 pandemic and mechanical ventilation: facing the present, designing the future. J Bras Pneumol, 2020.","journal-title":"J Bras Pneumol"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.09257"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/08850666211024139"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.01420"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1950.2.11.592"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.4103\/0972-5229.112149"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.00966"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181d74f71"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.10550334"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0847-0"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/039139880502801013"},{"issue":"5","key":"e_1_3_2_14_2","first-page":"365","article-title":"Adaptive support ventilation (ASV)","volume":"68","author":"Brunner JX","year":"2002","unstructured":"Brunner JX, , Iotti GA. 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