{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T03:22:03Z","timestamp":1784604123525,"version":"3.55.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respir Care"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Awake prone positioning (PP) reduces need for intubation for patients with COVID-19 with acute respiratory failure. We investigated the hemodynamic effects of awake PP in non-ventilated subjects with COVID-19 acute respiratory failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>We conducted a single-center prospective cohort study. Adult hypoxemic subjects with COVID-19 not requiring invasive mechanical ventilation receiving at least one PP session were included. Hemodynamic assessment was done with transthoracic echocardiography before, during, and after a PP session.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Twenty-six subjects were included. We observed a significant and reversible increase in cardiac index (CI) during PP compared to supine position (SP): 3.0 \u00b1 0.8 L\/min\/m\n                      <jats:sup>2<\/jats:sup>\n                      in PP, 2.5 \u00b1 0.6 L\/min\/m\n                      <jats:sup>2<\/jats:sup>\n                      before PP (SP1), and 2.6 \u00b1 0.5 L\/min\/m\n                      <jats:sup>2<\/jats:sup>\n                      after PP (SP2\n                      <jats:italic toggle=\"yes\">, P<\/jats:italic>\n                      &lt; .001). A significant improvement in right ventricular (RV) systolic function was also evidenced during PP: The RV fractional area change was 36 \u00b1 10% in SP1, 46 \u00b1 10% during PP, and 35 \u00b1 8% in SP2 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001). There was no significant difference in P\n                      <jats:sub>\n                        aO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      \/F\n                      <jats:sub>\n                        IO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:sub>\n                      and breathing frequency.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>CI and RV systolic function are improved by awake PP in non-ventilated subjects with COVID-19 with acute respiratory failure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4187\/respcare.10597","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T22:40:13Z","timestamp":1684968013000},"page":"713-720","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Hemodynamic Effects of Awake Prone Positioning With COVID-19 Acute Respiratory Failure"],"prefix":"10.1177","volume":"68","author":[{"given":"Matthias","family":"Jacquet-Lagr\u00e8ze","sequence":"first","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France; Facult\u00e9 de m\u00e9decine Lyon Est, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France; and CarMeN Laboratory, Inserm UMR 1060, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakaria","family":"Riad","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France; and Facult\u00e9 de m\u00e9decine Lyon Est, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Portran","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Chesnel","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9mi","family":"Schweizer","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Ferarris","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France; and Facult\u00e9 de m\u00e9decine Lyon Est, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Jacquemet","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Ruste","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France; and Facult\u00e9 de m\u00e9decine Lyon Est, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Fellahi","sequence":"additional","affiliation":[{"name":"Service d\u2019anesth\u00e9sie-r\u00e9animation, H\u00f4pital cardiologique Louis Pradel, Hospices Civils de Lyon, Bron, France; Facult\u00e9 de m\u00e9decine Lyon Est, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France; and CarMeN Laboratory, Inserm UMR 1060, Universit\u00e9 Claude Bernard Lyon 1, Lyon, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198906000-00002"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.5.9901037"},{"issue":"4","key":"e_1_3_2_4_2","first-page":"528","article-title":"Regional intrapulmonary gas distribution in awake and anesthetized-paralyzed prone man","volume":"45","author":"Rehder K","year":"1978","unstructured":"Rehder K, , Knopp TJ, , Sessler AD. 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