{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T22:43:15Z","timestamp":1772750595606,"version":"3.50.1"},"reference-count":0,"publisher":"Canadian Society of Healthcare-Systems Pharmacy","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJHP"],"abstract":"<jats:p>Background: Opioids are a common treatment for older adults living with pain. Given high rates of polypharmacy and chronic comorbidities, older adults are at risk of opioid overdose. Evidence is now available that take-home naloxone (THN) supports reduction of opioid-related harms. It is unknown what THN initiatives are available for older adults, especially those living with chronic pain.\nObjective: To summarize the literature regarding THN, with a focus on older adults using opioids for pain, including facilitators of and barriers to THN access, knowledge gaps, and pharmacist-led initiatives.\nData Sources: A scoping review, guided by an established framework and PRISMA-ScR guidelines, was performed. Methods involved searching 6 bibliographic databases (MEDLINE, Embase, Scopus, APA PsycINFO, Web of Science Core Collection, and PubMed), reference harvesting, and citation tracking. Searches were conducted up to March 2023, with no date limits applied; only English publications were included.\nStudy Selection and Data Extraction: Study eligibility was determined according to preset criteria, including age; discrepancies were resolved by discussion and consensus. Data were extracted and categorized through thematic analysis.\nData Synthesis: Four studies met the eligibility criteria. All 4 studies detailed THN programs in primary care settings involving older adults taking opioids for pain management. Two of the studies highlighted patient-specific risk factors for opioid overdose, including concomitant use of benzodiazepines and\/or gabapentinoids, mean morphine milligram equivalents per day of at least 50, and previous opioid overdose. Two of the studies assessed patient knowledge of opioid overdose management and attitudes toward THN. Educational programs increased patients\u2019 interest in THN.\nConclusions: The literature about THN for older adults living with pain is limited, and no literature was found on pharmacist-led initiatives in this area. Future research on THN provision for older adults, including pharmacist-led initiatives, could help to optimize care for older adults living with pain.\nKeywords: take-home naloxone, older adults, pain, opioids, harm reduction, special population\nR\u00c9SUM\u00c9\nContexte : Les opio\u00efdes sont un traitement courant pour les personnes \u00e2g\u00e9es souffrant de douleur. Compte tenu des taux \u00e9lev\u00e9s de polypharmacie et de comorbidit\u00e9s chroniques, les personnes \u00e2g\u00e9es courent un risque de surdose d\u2019opio\u00efdes. Il est d\u00e9sormais prouv\u00e9 que la distribution de trousses de naloxone contribue \u00e0 la r\u00e9duction des m\u00e9faits li\u00e9s aux opio\u00efdes. On ne sait pas quelles initiatives de distribution de trousses de naloxone existent pour les personnes \u00e2g\u00e9es, en particulier celles souffrant de douleurs chroniques.\nObjectif : R\u00e9sumer la documentation concernant la distribution des trousses de naloxone chez les personnes \u00e2g\u00e9es qui utilisent des opio\u00efdes contre la douleur, y compris les facilitateurs et les obstacles \u00e0 l\u2019acc\u00e8s aux trousses, les lacunes dans les connaissances et les initiatives men\u00e9es par les pharmaciens.\nSources des donn\u00e9es : Un examen de la port\u00e9e, guid\u00e9 par un cadre \u00e9prouv\u00e9 et les lignes directrices PRISMA-ScR, a \u00e9t\u00e9 r\u00e9alis\u00e9. Les m\u00e9thodes impliquaient la recherche dans 6 bases de donn\u00e9es bibliographiques (MEDLINE, Embase, Scopus, APA PsycINFO, Web of Science Core Collection et PubMed), la r\u00e9colte de r\u00e9f\u00e9rences et le suivi des citations. Les recherches ont \u00e9t\u00e9 effectu\u00e9es jusqu\u2019en mars 2023, sans limites quant \u00e0 la date; seules les publications en anglais ont \u00e9t\u00e9 incluses.\nS\u00e9lection des \u00e9tudes et extraction des donn\u00e9es : L\u2019admissibilit\u00e9 \u00e0 l\u2019\u00e9tude a \u00e9t\u00e9 d\u00e9termin\u00e9e selon des crit\u00e8res pr\u00e9d\u00e9finis, notamment l\u2019\u00e2ge; les divergences ont \u00e9t\u00e9 r\u00e9solues par discussion et consensus. Les donn\u00e9es ont \u00e9t\u00e9 extraites et cat\u00e9goris\u00e9es gr\u00e2ce \u00e0 une analyse th\u00e9matique.\nSynth\u00e8se des donn\u00e9es : Quatre \u00e9tudes r\u00e9pondaient aux crit\u00e8res d\u2019admissibilit\u00e9. Les 4 \u00e9tudes ont d\u00e9taill\u00e9 des programmes de distribution de trousses de naloxone dans des \u00e9tablissements de soins primaires chez les personnes \u00e2g\u00e9es prenant des opio\u00efdes pour g\u00e9rer la douleur. Deux des \u00e9tudes ont mis en \u00e9vidence des facteurs de risque sp\u00e9cifiques aux patients en mati\u00e8re de surdosage aux opio\u00efdes, notamment l\u2019utilisation concomitante de benzodiaz\u00e9pines et\/ou de gabapentino\u00efdes, une moyenne d\u2019\u00e9quivalents en milligrammes de morphine par jour d\u2019au moins 50 et un surdosage ant\u00e9rieur aux opio\u00efdes. Deux des \u00e9tudes ont \u00e9valu\u00e9 les connaissances des patients en mati\u00e8re de gestion des surdosages aux opio\u00efdes et leur attitude envers la distribution de trousses de naloxone. Les programmes \u00e9ducatifs ont accru l\u2019int\u00e9r\u00eat des patients pour les trousses de naloxone.\nConclusions : La documentation sur la distribution de trousses de naloxone chez les personnes \u00e2g\u00e9es souffrant de douleur est limit\u00e9e et aucune litt\u00e9rature n\u2019a \u00e9t\u00e9 trouv\u00e9e sur les initiatives men\u00e9es par les pharmaciens dans ce domaine. Les recherches futures sur la distribution de trousses de naloxone aux personnes \u00e2g\u00e9es, y compris les initiatives men\u00e9es par des pharmaciens, pourraient contribuer \u00e0 optimiser les soins aux personnes \u00e2g\u00e9es souffrant de douleur.\nMots cl\u00e9s : trousses de naloxone, personnes \u00e2g\u00e9es, douleur, opio\u00efdes, r\u00e9duction des m\u00e9faits, population particuli\u00e8re\"<\/jats:p>","DOI":"10.4212\/cjhp.3506","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T17:31:23Z","timestamp":1710351083000},"source":"Crossref","is-referenced-by-count":2,"title":["Take-Home Naloxone Access and Use among Older Adults Living with Pain: A Scoping Review"],"prefix":"10.4212","volume":"77","author":[{"given":"Ryan","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Yakiwchuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6141-0439","authenticated-orcid":false,"given":"Katelyn","family":"Halpape","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2732","published-online":{"date-parts":[[2024,3,13]]},"container-title":["Canadian Journal of Hospital Pharmacy"],"original-title":[],"link":[{"URL":"https:\/\/www.cjhp-online.ca\/index.php\/cjhp\/article\/download\/3506\/5227","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.cjhp-online.ca\/index.php\/cjhp\/article\/download\/3506\/5240","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.cjhp-online.ca\/index.php\/cjhp\/article\/download\/3506\/5227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T17:31:24Z","timestamp":1710351084000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cjhp-online.ca\/index.php\/cjhp\/article\/view\/3506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,13]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1,10]]}},"URL":"https:\/\/doi.org\/10.4212\/cjhp.3506","relation":{},"ISSN":["1920-2903","0008-4123"],"issn-type":[{"value":"1920-2903","type":"electronic"},{"value":"0008-4123","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3,13]]}}}