{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:09:33Z","timestamp":1792253373696,"version":"4.4.0"},"reference-count":50,"publisher":"The Korean Geriatrics Society","issue":"1","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"JSPS-KAKENHI","award":["19H03979"],"award-info":[{"award-number":["19H03979"]}]}],"content-domain":{"domain":["e-agmr.org"],"crossmark-restriction":true},"short-container-title":["Ann Geriatr Med Res"],"published-print":{"date-parts":[[2024,3,31]]},"abstract":"<jats:p>Background: Although the relationship between medication status, symptomatology, and outcomes has been evaluated, data on the prevalence of polypharmacy and potentially inappropriate medications (PIMs) and the association of polypharmacy and PIMs with swallowing function during follow-up are limited among hospitalized patients aged \u226565 years with dysphagia. Methods: In this 19\u2010center cohort study, we registered 467 inpatients aged \u226565 years and evaluated those with the Food Intake LEVEL Scale (FILS) scores \u22648 between November 2019 and March 2021. Polypharmacy was defined as prescribing \u22655 medications and PIMs were identified based on the 2023 Updated Beers Criteria. We applied a generalized linear regression model to examine the association of polypharmacy and PIMs with FILS score at discharge.Results: We analyzed 399 participants (median age, 83.0 years; males, 49.8%). The median follow\u2010up was 51.0 days (interquartile range, 22.0\u201384.0 days). Polypharmacy and PIMs were present in 67.7% of and 56.1% of patients, respectively. After adjusting for covariates, neither polypharmacy (\u03b2 = 0.05; 95% confidence interval [CI], -0.04\u20130.13, p=0.30) nor non\u2010steroidal anti\u2010inflammatory medications (\u03b2 = 0.09; 95% CI, -0.02\u20130.19; p=0.10) were significantly associated with FILS score at discharge.Conclusions: The results of this study indicated a high proportion of polypharmacy and PIMs among inpatients aged \u226565 years with dysphagia. Although these prescribed conditions were not significantly associated with swallowing function at discharge, our findings suggest the importance of regularly reviewing medications to ensure the appropriateness of prescriptions when managing older inpatients.<\/jats:p>","DOI":"10.4235\/agmr.23.0203","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T06:47:30Z","timestamp":1705474050000},"page":"86-94","update-policy":"https:\/\/doi.org\/10.4235\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Polypharmacy, Potentially Inappropriate Medications, and Dysphagia in Older Inpatients: A Multi-Center Cohort 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