{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T04:12:21Z","timestamp":1767067941329,"version":"3.48.0"},"reference-count":33,"publisher":"The Korean Geriatrics Society","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Malaysian Ministry of Higher Education Long-Term Research Grant Scheme","award":["LRGS\/1\/2019\/UM\/\/1\/1"],"award-info":[{"award-number":["LRGS\/1\/2019\/UM\/\/1\/1"]}]}],"content-domain":{"domain":["e-agmr.org"],"crossmark-restriction":true},"short-container-title":["Ann Geriatr Med Res"],"published-print":{"date-parts":[[2025,12,31]]},"abstract":"<jats:p>Background: While adiposity has been found to be protective against adverse outcomes in older adults, the role of muscle in this association remains underexplored. This study sought to evaluate sex-specific mortality associated with available adiposity indices in older adults and the potential role of muscle strength in this relationship.Methods: Individuals aged \u226555 years were recruited from 2013 to 2015. Adiposity indices obtained were body mass index (BMI), percentage body fat (%BF), waist-to-hip ratio (WHR), and waist circumference (WC). Vital status up to June 2022 was determined through the National Registry Department. Results: Of the 1,347 included participants, mean age of 68.45\u00b17.21 years, 57.1% female, and 11.2% deaths were recorded. Male who were underweight had increased mortality compared to male with normal BMI (hazard ratio [HR]=3.17, 95% confidence interval [CI] 1.35\u20137.47). Mortality was greater in male with %BF within the highest quartile (Q4) compared to the lowest quartile (Q1) (HR=4.72, 95% CI 2.07\u201310.78). Increased mortality in both male and female in Q4 for WHR compared to Q1 was influenced by age, as was increased mortality in female in Q4 for %BF. WC did not predict mortality in male or female. Increased mortality risk was present in male with normal muscle strength and increased %BF, and reduced muscle strength in male with low BMI.Conclusions: Adiposity measured with BMI, WHR and WC had limited value in determining mortality risk at 9-year follow-up among individuals aged \u226555 years. Increased mortality was, however, observed in male with higher %BF but this could not be attributed to muscle strength.<\/jats:p>","DOI":"10.4235\/agmr.24.0167","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:17:52Z","timestamp":1760663872000},"page":"495-505","update-policy":"https:\/\/doi.org\/10.4235\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sex-specific All-cause Mortality is Associated with Adiposity in the Malaysian Elders Longitudinal Research (MELoR) Study"],"prefix":"10.4235","volume":"29","author":[{"given":"Nurul Nabilah Akmal","family":"Hashim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumaiyah","family":"Mat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phyo 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