{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T09:10:16Z","timestamp":1759137016376,"version":"3.44.0"},"reference-count":50,"publisher":"The Korean Geriatrics Society","issue":"3","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["e-agmr.org"],"crossmark-restriction":true},"short-container-title":["Ann Geriatr Med Res"],"published-print":{"date-parts":[[2025,9,30]]},"abstract":"<jats:p>Background: Phase angle (PhA) is a potential indicator of nutritional status and functional outcomes. However, optimal regional PhA cutoff values for predicting activities of daily living (ADL) post-stroke are unclear. We aimed to determine these cutoffs and assess whether PhA adds prognostic value to established clinical models.Methods: In this retrospective cohort study, stroke patients undergoing inpatient rehabilitation had body composition and PhA measured via multi-frequency bioelectrical impedance analysis. The primary outcome was ADL independence at discharge (motor Functional Independence Measure &gt;78). Receiver operating characteristic (ROC) curves identified optimal PhA cutoffs; logistic regression assessed their predictive value, adjusting for confounders. Incremental discriminative ability was evaluated using area under the ROC curve (AUC) comparisons with DeLong\u2019s test.Results: Among 1,080 patients (median age, 75.6 years; 54.1% men), optimal PhA cutoffs were: whole-body (women 3.90\u00b0, men 4.60\u00b0), non-paretic upper limb (4.45\u00b0, 4.90\u00b0), and non-paretic lower limb (4.00\u00b0, 4.80\u00b0). Higher PhA values above these cutoffs were independently associated with ADL independence (all p&lt;0.05). Adding whole-body PhA to the baseline model improved AUC from 0.937 to 0.970 (\u0394AUC=0.033; p=0.011); significant gains were observed for limb PhA.Conclusions: Optimal site-specific PhA cutoffs predict ADL independence at discharge in post-stroke patients. PhA provides significant incremental prognostic value beyond established clinical models, supporting its use in tailoring rehabilitation strategies.<\/jats:p>","DOI":"10.4235\/agmr.25.0028","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:57:06Z","timestamp":1756288626000},"page":"403-413","update-policy":"https:\/\/doi.org\/10.4235\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimal Cutoff Values of Site-Specific Phase Angle for Predicting Independence in Activities of Daily Living in Post-stroke Patients"],"prefix":"10.4235","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7545-4179","authenticated-orcid":true,"given":"Yoshihiro","family":"Yoshimura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidetaka","family":"Wakabayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumihiko","family":"Nagano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayaka","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayuri","family":"Shimazu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Shiraishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifumi","family":"Kido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Bise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takenori","family":"Hamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouki","family":"Yoneda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2749","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2012.05.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2023.12.001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-022-09757-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.10.048"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3390\/nu15061409"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3791\/65660"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13820"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2490\/prm.20230044"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4235\/agmr.23.0212"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.12740\/pp\/67500"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.105941"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12860"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18094741"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2703"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2020.111091"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-020-1439-8"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.11336\/jjcrs.13.41"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2024.04.027"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000258355.23810.c6"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/mrr.0b013e32832a62ad"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/s0003-9993(96)90184-7"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s41999-020-00446-4"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14202"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-022-01416-5"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-024-05272-x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2023.08.018"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1177\/14791641231223701"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.2490\/prm.20220021"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1177\/000313481708300619"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1080\/16501970510044034"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3109\/09638289509166622"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-021-01841-y"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.4235\/agmr.24.0020"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2021.02.018"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.2490\/prm.20180011"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.252.15"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.3390\/nu14204251"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1002\/jgf2.509"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-022-09775-0"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1298\/ptr.e9914"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2024.03.028"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-023-09803-7"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2021.111397"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2023.112181"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14651"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1007\/s41999-023-00833-7"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1097\/mco.0000000000000787"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.31662\/jmaj.2021-0201"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1002\/jgf2.549"}],"container-title":["Annals of Geriatric Medicine and Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-agmr.org\/upload\/pdf\/agmr-25-0028.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-agmr.org\/journal\/view.php?doi=10.4235\/agmr.25.0028","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-agmr.org\/upload\/pdf\/agmr-25-0028.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T08:31:20Z","timestamp":1759134680000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-agmr.org\/journal\/view.php?doi=10.4235\/agmr.25.0028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"URL":"https:\/\/doi.org\/10.4235\/agmr.25.0028","relation":{},"ISSN":["2508-4798","2508-4909"],"issn-type":[{"type":"print","value":"2508-4798"},{"type":"electronic","value":"2508-4909"}],"subject":[],"published":{"date-parts":[[2025,9,30]]},"assertion":[{"value":"2025-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-29","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}