{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:54:47Z","timestamp":1790751287687,"version":"4.1.0"},"reference-count":20,"publisher":"The Korean Geriatrics Society","issue":"3","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["22K17843"],"award-info":[{"award-number":["22K17843"]}]}],"content-domain":{"domain":["e-agmr.org"],"crossmark-restriction":true},"short-container-title":["Ann Geriatr Med Res"],"published-print":{"date-parts":[[2026,9,30]]},"abstract":"<jats:p>Background: In 2019, the European Working Group of Sarcopenia in Older People indicated the importance of assessing muscle mass and quality in diagnosing sarcopenia. The extracellular water- to-total body water ratio (ECW\/TBW) has recently attracted attention as an indicator of muscle quality. This study aimed to clarify the associations of ECW\/TBW and grip strength and gait speed in community-dwelling individuals in their 20s to 90s.Methods: This study employed a cross-sectional design. We enrolled 661 community-dwelling individuals (aged \u226520). The ECW\/ TBW was measured using multifrequency bioelectrical impedance analysis. Associations between grip strength, gait speed, and ECW\/TBW were analyzed separately for males and females using Spearman\u2019s correlation coefficient. Multiple linear regression analyses were conducted to examine factors associated with grip strength and gait speed.Results: Correlation analyses revealed significant negative correlations between ECW\/TBW and grip strength (males: \u03c1=-0.413, p&lt;0.001; females: \u03c1=-0.384, p&lt;0.001) and gait speed (males: \u03c1=-0.122, p=0.037; females: \u03c1=-0.206, p&lt;0.001). In the multiple linear regression analysis, ECW\/TBW was significantly and independently associated with grip strength (males: \u03b2=-0.207, p=0.006; females: \u03b2=-0.215, p=0.001) and gait speed (males: \u03b2=-0.213, p=0.013; females: \u03b2=-0.305, p&lt;0.001).Conclusion: The present study identified negative associations between ECW\/TBW and both grip strength and gait speed among community-dwelling individuals in their 20s to 90s. Additionally, these associations were confirmed in males and females.<\/jats:p>","DOI":"10.4235\/agmr.26.0060","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T07:31:50Z","timestamp":1782372710000},"page":"371-378","update-policy":"https:\/\/doi.org\/10.4235\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Increased Extracellular-to-Total Body Water Ratio in Community-Dwelling Individuals in their 20s to 90s is Associated with Decreased Grip Strength and Gait Speed"],"prefix":"10.4235","volume":"30","author":[{"given":"Akemi","family":"Hioka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5815-8650","authenticated-orcid":true,"given":"Naoki","family":"Akazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Okawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Nagahiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2749","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afz046"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16372"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s41999-022-00652-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4235\/agmr.23.0101"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-017-3686-x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s11556-026-00402-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2024.01.007"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-020-01766-y"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2022.63.9.873"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2021.111175"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2011.12.006"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2012.02.018"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2017.03.013"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afaa070"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153583"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2012.00111"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/85.1.80"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2019.12.001"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2014.00008"}],"container-title":["Annals of Geriatric Medicine and Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-agmr.org\/upload\/pdf\/agmr-26-0060.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-agmr.org\/journal\/view.php?doi=10.4235\/agmr.26.0060","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-agmr.org\/upload\/pdf\/agmr-26-0060.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:54:53Z","timestamp":1790747693000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-agmr.org\/journal\/view.php?doi=10.4235\/agmr.26.0060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"URL":"https:\/\/doi.org\/10.4235\/agmr.26.0060","relation":{},"ISSN":["2508-4798","2508-4909"],"issn-type":[{"value":"2508-4798","type":"print"},{"value":"2508-4909","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"assertion":[{"value":"2026-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-25","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}