{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T08:19:42Z","timestamp":1781597982431,"version":"3.54.5"},"reference-count":33,"publisher":"Baishideng Publishing Group Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Diabetes"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>At present, the existing internal medicine drug treatment can alleviate the high glucose toxicity of patients to a certain extent, to explore the efficacy of laparoscopic jejunoileal side to side anastomosis in the treatment of type 2 diabetes, the report is as follows.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To investigate the effect of jejunoileal side-to-side anastomosis on metabolic parameters in patients with type 2 diabetes mellitus (T2DM).<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>We retrospectively analyzed the clinical data of 78 patients with T2DM who were treated via  jejunoileal lateral anastomosis. Metabolic indicators were collected preoperatively, as well as at 3 and 6 months postoperative. The metabolic indicators analyzed included body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), 2-hour blood glucose (PBG), glycated hemoglobin (HbA1c), fasting C-peptide, 2-hour C-peptide (PCP), fasting insulin (Fins), 2-hour insulin (Pins), insulin resistance index (HOMA-IR), \u03b2 Cellular function index (HOMA-\u03b2), alanine aminotransferase, aspartate aminotransferase, serum total cholesterol (TC), low-density lipoprotein cholesterol (L DL-C), triglycerides (TG), high-density lipoprotein, and uric acid (UA) levels.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>SBP, DBP, PBG, HbA1c, LDL-C, and TG were all significantly lower 3 months postoperative vs  preoperative values; body weight, BMI, SBP, DBP, FBG, PBG, HbA1c, TC, TG, UA, and HOMA-IR values were all significantly lower 6 months postoperative vs  at 3 months; and PCP, Fins, Pins, and HOMA-\u03b2 were all significantly higher 6 months postoperative vs  at 3 months (all P  &lt; 0.05).<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Side-to-side anastomosis of the jejunum and ileum can effectively treat T2DM and improve the metabolic index levels associated with it.<\/jats:p>","DOI":"10.4239\/wjd.v16.i1.99526","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T07:07:07Z","timestamp":1732864027000},"source":"Crossref","is-referenced-by-count":5,"title":["Clinical study on the effect of jejunoileal side-to-side anastomosis on metabolic parameters in patients with type 2 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