{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:41:38Z","timestamp":1773326498462,"version":"3.50.1"},"reference-count":30,"publisher":"Baishideng Publishing Group Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Diabetes"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>The prevalence and clinical characteristics of chronic kidney disease (CKD) among patients with ketosis-onset diabetes (also known as ketosis-prone diabetes) remain unclear. Furthermore, the classification of ketosis-onset diabetes remains controversial and requires further investigation.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To investigate the prevalence and clinical features of CKD in patients with newly diagnosed ketosis-onset diabetes.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>This real-world study included 217 patients with type 1 diabetes mellitus (T1DM), 698 with ketosis-onset diabetes, and 993 with non-ketotic T2DM. The prevalence and clinical characteristics of CKD were compared among the three groups. Risk factors associated with CKD were evaluated using binary logistic regression for each group.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>After adjusting for age and sex, the prevalence of CKD among patients with ketosis-onset diabetes (17.8%) was significantly higher than that in those with T1DM (8.3%, P  = 0.007), but was not statistically different compared to those with non-ketotic T2DM (21.7%, P  = 0.214). Furthermore, some risk factors for CKD, including age, and serum uric acid and C-reactive protein levels, in patients with ketosis-onset diabetes were similar to those with T2DM, but significantly different from those with T1DM.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>The prevalence, clinical characteristics, and risk factors for CKD among patients with ketosis-onset diabetes were more similar to those with non-ketotic T2DM but considerably different from those with T1DM. These findings further support the classification of ketosis-onset diabetes as a subtype of T2DM rather than idiopathic T1DM.<\/jats:p>","DOI":"10.4239\/wjd.v16.i3.100059","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T20:02:58Z","timestamp":1737403378000},"source":"Crossref","is-referenced-by-count":1,"title":["Prevalence and clinical characteristics of chronic kidney disease among patients with newly diagnosed ketosis-onset diabetes"],"prefix":"10.4239","volume":"16","author":[{"given":"Meng-Han","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Man-Rong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Jie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Yun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian-Xi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9282.66.S1.3"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1080\/10641963.2023.2203411"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.pop.2008.01.008"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.2337\/dbi20-0040"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-7-415"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2016.03.020"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-32983-1"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.18"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7854294"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.4172\/2155-6156.1000175"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.3.645"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-S002"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-001-0739-8"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1210\/er.2007-0026"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2006.01.005"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2840-12-18"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2018.03.002"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1186\/s13098-019-0426-x"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/2315607"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5000061"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.672350"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2010.03049.x"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2008.128"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1080\/16089677.2017.1417779"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2018.09.018"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3197"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S421203"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S349467"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2011.11.009"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-0857"}],"container-title":["World Journal of Diabetes"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-9358\/full\/v16\/i3\/100059.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-9358\/full\/v16\/i3\/100059.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T20:03:23Z","timestamp":1737403403000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-9358\/full\/v16\/i3\/100059.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,15]]},"references-count":30,"journal-issue":{"issue":"3"},"alternative-id":["100059"],"URL":"https:\/\/doi.org\/10.4239\/wjd.v16.i3.100059","relation":{},"ISSN":["1948-9358"],"issn-type":[{"value":"1948-9358","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,15]]}}}