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Indeed, the gut microbiota has emerged as a promising therapeutic approach for treating type 2 diabetes and related diseases. However, there is few of literatures specifically discussing the relationship between gut microbiota and diabetic wounds. This review aims to explore the potential role of the gut microbiota, especially probiotics, and its associated byproducts such as short chain fatty acids, bile acids, hydrogen sulfide, and tryptophan metabolites on wound healing to provide fresh insights and novel perspectives for the treatment of chronic wounds in diabetes.<\/jats:p>","DOI":"10.4239\/wjd.v16.i5.98788","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:29:57Z","timestamp":1745468997000},"source":"Crossref","is-referenced-by-count":9,"title":["Targeting gut microbiota and its associated metabolites as a potential strategy for promoting would healing in 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