{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T11:15:33Z","timestamp":1722251733529},"reference-count":17,"publisher":"Baishideng Publishing Group Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastrointest Surg"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>The maximum outer diameter (MOD) of the appendix is an essential parameter for diagnosing acute appendicitis, but there is space for improvement in ultrasound (US) diagnostic performance.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To investigate whether combining the ratio of the cross diameters (RATIO) of the appendix with MOD of the appendix can enhance the diagnostic performance of acute appendicitis.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>A retrospective study was conducted, and medical records of 233 patients with acute appendicitis and 112 patients with a normal appendix were reviewed. The MOD and RATIO of the appendix were calculated and tested for their diagnostic performance of acute appendicitis, both individually and in combination.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>The RATIO for a normal appendix was 1.32 \u00b1 0.16, while for acute appendicitis it was 1.09 \u00b1 0.07. The cut-off value for RATIO was determined to be \u2264 1.18. The area under the receiver operating characteristic curve (AUC) for diagnosing acute appendicitis using RATIO \u2264 1.18 and MOD &gt; 6 mm was 0.870 and 0.652, respectively. There was a significant difference in AUC between RATIO \u2264 1.18 and MOD &gt; 6 mm (P  &lt; 0.0001). When comparing the combination of RATIO \u2264 1.18 and MOD &gt; 6 mm with MOD &gt; 6 mm alone, the combination showed increased specificity, positive predictive value (PPV), and AUC. However, the sensitivity and negative predictive value decreased.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Combining RATIO of the appendix \u2264 1.18 and MOD &gt; 6 mm can significantly improve the specificity, PPV, and AUC in the US diagnosis of acute appendicitis.<\/jats:p>","DOI":"10.4240\/wjgs.v16.i1.21","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T02:09:23Z","timestamp":1706148563000},"page":"21-28","source":"Crossref","is-referenced-by-count":1,"title":["Added value of ratio of cross diameters of the appendix in ultrasound diagnosis of acute appendicitis"],"prefix":"10.4240","volume":"16","author":[{"given":"Feng-Wa","family":"Gu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si-Ze","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,1,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.20502"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1055\/a-0824-6952"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.radi.2022.08.012"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000033397"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.218.3.r01fe20757"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2302021520"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000001278"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20807"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.12205"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.161.1.8517294"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.17.19321"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018180318"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.11152\/mu-2541"},{"key":"B14","unstructured":"Sezer TO, Gulece B, Zalluhoglu N, Gorgun M, Dogan S. Diagnostic value of ultrasonography in appendicitis. Adv Clin Exp Med 2012; 21: 633-636"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2261011496"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v14.i4.370"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1097\/RUQ.0000000000000536"}],"container-title":["World Journal of Gastrointestinal Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-9366\/full\/v16\/i1\/21.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-9366\/full\/v16\/i1\/21.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T02:09:35Z","timestamp":1706148575000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-9366\/full\/v16\/i1\/21.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,27]]},"references-count":17,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4240\/wjgs.v16.i1.21","relation":{},"ISSN":["1948-9366"],"issn-type":[{"value":"1948-9366","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1,27]]}}}