{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:28:43Z","timestamp":1790832523729,"version":"4.1.0"},"reference-count":32,"publisher":"Baishideng Publishing Group Inc.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastrointest Surg"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract, often requiring intestinal resection as a common treatment. However, recurrence after surgery is common. The anastomotic configuration after bowel resection appears to be associated with the recurrence of CD. Previous studies have suggested that the Kono-S anastomosis may help to reduce the recurrence rate. However, the results remain controversial. Therefore, evidence-based evidence is needed to prove the advantages of Kono-S anastomosis.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To measure the influence of anastomosis techniques on the long-term relapse rate of CD by conducting a meta-analysis.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>PubMed, Scopus, and Cochrane Library were searched until October 8, 2023. Patients who underwent intestinal resection due to CD were included. The intervention measures included Kono-S anastomosis, whereas the control group received traditional anastomosis such as end-to-end, end-to-side, and side-to-side anastomosis. Only randomized clinical trials and observational studies were included. The primary outcome measures were hospital stay post-surgery, overall postoperative complication incidence, the proportion of Clavien-Dindo grade IIIa or higher, overall postoperative recurrence rate, and Rutgeerts score.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>From 2011 to 2023, six articles met the inclusion and exclusion criteria. The results indicated that Kono-S anastomosis can reduce the hospital stay post-surgery of patients with CD [MD = -0.26, 95%CI: -0.42 to -0.10, P  = 0.002] than other traditional anastomosis methods. Compared to other traditional anastomosis methods, Kono-S anastomosis can significantly reduce the total recurrence rate [MD = 0.40, 95%CI: 0.17 to 0.98, P  = 0.05] and postoperative Rutgeerts score [MD = -0.81, 95%CI: -0.96 to -0.66, P  &lt; 0.001] in patients with CD. However, there is no significant disparity in the overall occurrence of postoperative complications and the proportion of Clavien-Dindo \u2265 IIIa.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Kono-S anastomosis has the potential to expedite the recuperation of CD and diminish relapse hazards; however, additional larger trials are necessary to authenticate its effectiveness.<\/jats:p>","DOI":"10.4240\/wjgs.v16.i4.1165","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T08:00:03Z","timestamp":1713686403000},"page":"1165-1175","source":"Crossref","is-referenced-by-count":3,"title":["Impact of different anastomosis methods on post-recurrence after intestinal resection for Crohn's disease: A meta-analysis"],"prefix":"10.4240","volume":"16","author":[{"given":"Zheng-Zuo","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Hua","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gui-Ping","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2024,4,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i1.31"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31711-1"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32448-0"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2017.05.004"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/s13062-020-00280-5"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2017.10.036"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.25122\/jml-2018-0075"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjz158"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000638"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1586\/egh.09.13"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-021-03857-2"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-021-02551-3"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-021-07205-w"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-020-01998-6"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-018-4012-6"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)90613-6"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1177\/0962280216669183"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izad214"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11236915"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjad176"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e318208b90f"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003821"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15136"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-1905-7"},{"key":"B26","unstructured":"Fornaro R, Caristo G, Stratta E, Oliva A, Giovinazzo D, Mascherini M, Frascio M. 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