{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:45:33Z","timestamp":1787067933312,"version":"build-2736575974"},"reference-count":43,"publisher":"Baishideng Publishing Group Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastrointest Surg"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n                  <jats:p>Explore the risk factors of gastrointestinal dysfunction after gastrointestinal tumor surgery and to provide evidence for the prevention and intervention of gastrointestinal dysfunction in patients with gastrointestinal tumor surgery.<\/jats:p>\n                  <jats:p>AIM<\/jats:p>\n                  <jats:p>To investigate the potential risk factors for gastrointestinal dysfunction following gastrointestinal tumor surgery and to present information supporting the prevention and management of gastrointestinal dysfunction in surgery patients.<\/jats:p>\n                  <jats:p>METHODS<\/jats:p>\n                  <jats:p>Systematically searched the relevant literature from PubMed, Web of Science, Cochrane Library, Embase, CNKI, China Biomedical Database, Wanfang Database, and Weipu Chinese Journal Database self-established until October 1, 2022. Review Manager 5.3 software was used for meta-analysis after two researchers independently screened literature, extracted data, and evaluated the risk of bias in the included studies.<\/jats:p>\n                  <jats:p>RESULTS<\/jats:p>\n                  <jats:p>A total of 23 pieces of literature were included, the quality of which was medium or above, and the total sample size was 43878. The results of meta-analysis showed that the patients were male (OR = 1.58, 95%CI: 1.25-2.01, P  = 0.002) and \u2265 60 years old (OR = 2.60, 95%CI: 1.76-2.87, P  &lt; 0.001), physical index \u2265 25.3 kg\/m2 (OR = 1.6, 95%CI: 1.00-1. 12, P  = 0.040), smoking history (OR = 1.89, 95%CI: 1.31-2.73, P  &lt; 0.001), chronic obstructive pulmonary disease (OR = 1.49, 95%CI: 1.22-1.83, P  &lt; 0.001), enterostomy (OR = 1.47, 95%CI: 1.26-1.70, P  &lt; 0.001), history of abdominal surgery (OR = 2.90, 95%CI: 1.67-5.03, P  &lt; 0.001), surgical site (OR = 1.2, 95%CI: 1.40-2.62, P  &lt; 0.001), operation method (OR = 1.68, 95%CI: 1.08-2.62, P  = 0.020), operation duration (OR = 2.65, 95%CI: 1.92-3.67, P  &lt; 0.001), abdominal adhesion grade (OR = 2.52, 95%CI: 1.90-3.56, P  &lt; 0.001), postoperative opioid history (OR = 5.35, 95%CI: 3.29-8.71, P  &lt; 0.001), tumor TNM staging (OR = 2.58, 95%CI: 1.84-3.62, P  &lt; 0.001), postoperative blood transfusion (OR = 2.92, 95%CI: 0.88-9.73, P  = 0.010) is a risk factor for postoperative gastrointestinal dysfunction in patients with gastrointestinal tumors.<\/jats:p>\n                  <jats:p>CONCLUSION<\/jats:p>\n                  <jats:p>There are many factors affecting gastrointestinal dysfunction in gastrointestinal patients after surgery. Clinical staff should identify relevant risk factors early and implement targeted intervention measures on the basis of personalized assessment to improve the clinical prognosis of patients.<\/jats:p>","DOI":"10.4240\/wjgs.v16.i5.1420","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T22:51:51Z","timestamp":1716418311000},"page":"1420-1429","source":"Crossref","is-referenced-by-count":6,"title":["Prognostic factors associated with gastrointestinal dysfunction after gastrointestinal tumor surgery: A meta-analysis"],"prefix":"10.4240","volume":"16","author":[{"given":"Jia","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2024,5,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.07.015"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1177\/00031348241227200"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.08.022"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2021.667124"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S401161"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202860"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2023.102938"},{"key":"B8","unstructured":"Franko J, O'Connell BG, Mehall JR, Harper SG, Nejman JH, Zebley DM, Fassler SA. 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