{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T12:48:29Z","timestamp":1770468509607,"version":"3.49.0"},"reference-count":28,"publisher":"Baishideng Publishing Group Inc.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastrointest Surg"],"abstract":"<jats:p>The recent study by Chen et al , published in the World Journal of Gastroenterology , introduces a groundbreaking assessment tool-the preoperative systemic immune-inflammation index\/albumin (SII\/ALB) ratio-for patients with hepatocellular carcinoma (HCC) undergoing curative resection. This study not only establishes the independent prognostic significance of the SII\/ALB ratio but also incorporates it into a predictive nomogram, enhancing its utility for clinical decision-making. The SII\/ALB ratio, by integrating inflammatory and nutritional biomarkers, offers a novel lens through which the prognosis of HCC patients can be viewed, suggesting a more tailored approach to patient management. The development of the nomogram, validated for its accuracy in predicting patient outcomes, marks a pivotal advance, potentially guiding surgical decisions and postoperative care. However, the study's focus on a single-center cohort prompts the need for validation in a broader, more diverse patient population to ensure its applicability across various clinical settings. Moreover, longitudinal studies could elucidate the dynamic changes in SII\/ALB post-surgery, offering insights into its potential as a continuous monitor for recurrence and long-term survival. This abstract aim to underscore the critical findings of Chen et al 's study while calling for further research to explore the full potential of the SII\/ALB ratio in the global management of hepatocellular carcinoma.<\/jats:p>","DOI":"10.4240\/wjgs.v17.i2.102261","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T20:02:33Z","timestamp":1737403353000},"source":"Crossref","is-referenced-by-count":0,"title":["Harnessing the prognostic power of preoperative systemic immune-inflammation index\/albumin ratio in hepatocellular carcinoma resection"],"prefix":"10.4240","volume":"17","author":[{"given":"Zhao-Nan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan-Shan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si-Xiang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Dong","family":"Miao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v30.i48.5130"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0305119"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005865"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-020-00884-8"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i34.6261"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e15156"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-024-12655-2"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2021.101204"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.963060"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.2196\/59762"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32792"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1108\/IJHCQA-11-2019-0195"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003620"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0442"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2023.22296"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_1080_19"},{"key":"B17","doi-asserted-by":"crossref","unstructured":"Teng W, Cheng TA, Lin PT, Lin CC, Lin CY, Lin SM. Combination of systemic immune-inflammation index and albumin-bilirubin grade predict prognosis of regorafenib in unresectable hepatocellular carcinoma. Am J Cancer Res 2023; 2702-2713","DOI":"10.1016\/S0168-8278(22)01125-4"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S449441"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-023-01035-y"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmoop.2021.100118"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24087640"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14220"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3390\/ph6080929"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2013.03.010"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1186\/s40795-023-00694-0"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1515\/med-2024-1023"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2021.1970864"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2023.1118403"}],"container-title":["World Journal of Gastrointestinal Surgery"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-9366\/full\/v17\/i2\/102261.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-9366\/full\/v17\/i2\/102261.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T20:03:31Z","timestamp":1737403411000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-9366\/full\/v17\/i2\/102261.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,27]]},"references-count":28,"journal-issue":{"issue":"2"},"alternative-id":["102261"],"URL":"https:\/\/doi.org\/10.4240\/wjgs.v17.i2.102261","relation":{},"ISSN":["1948-9366"],"issn-type":[{"value":"1948-9366","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,27]]}}}