{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:58:47Z","timestamp":1792022327709,"version":"4.4.0"},"reference-count":137,"publisher":"Europa Digital & Publishing","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EuroIntervention"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.4244\/eijy20m07_01","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T10:45:59Z","timestamp":1611139559000},"page":"1049-1069","source":"Crossref","is-referenced-by-count":240,"title":["An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group"],"prefix":"10.4244","volume":"16","author":[{"given":"Vijay","family":"Kunadian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaide","family":"Chieffo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo G.","family":"Camici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Escaned","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela H.E.M.","family":"Maas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Prescott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Karam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolande","family":"Appelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Fraccaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gill Louise","family":"Buchanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Manzo-Silberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Al-Lamee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Regar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Lansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Dawn","family":"Abbott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Badimon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk J.","family":"Duncker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana","family":"Mehran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Capodanno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Baumbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2774","reference":[{"key":"60080988726e9-0","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31012-1"},{"key":"60080988726e9-1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz425"},{"key":"60080988726e9-2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy806"},{"key":"60080988726e9-3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra061889"},{"key":"60080988726e9-4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr331"},{"key":"60080988726e9-5","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-013-0568-z"},{"key":"60080988726e9-6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.02.082"},{"key":"60080988726e9-7","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-311446"},{"key":"60080988726e9-8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028782"},{"key":"60080988726e9-9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.113.000978"},{"key":"60080988726e9-10","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.031907"},{"key":"60080988726e9-11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2010.00598.x"},{"key":"60080988726e9-12","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2014.160"},{"key":"60080988726e9-13","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht513"},{"key":"60080988726e9-14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.08.068"},{"key":"60080988726e9-15","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-017-1136-9"},{"key":"60080988726e9-16","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(59)90003-8"},{"key":"60080988726e9-17","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv351"},{"key":"60080988726e9-18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.08.1056"},{"key":"60080988726e9-19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1415516"},{"key":"60080988726e9-20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.01.054"},{"key":"60080988726e9-21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.04.002"},{"key":"60080988726e9-22","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.003064"},{"key":"60080988726e9-23","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.002857"},{"key":"60080988726e9-24","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012636"},{"key":"60080988726e9-25","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.008507"},{"key":"60080988726e9-26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.06.017"},{"key":"60080988726e9-27","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.5.1094"},{"key":"60080988726e9-28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.11.017"},{"key":"60080988726e9-29","first-page":"100370","article-title":"Pro-inflammatory biomarkers in women with non-obstructive angina pectoris and coronary microvascular dysfunction.","volume":"24","author":"Schroder J","year":"2019","journal-title":"Int J Cardiol Heart Vasc"},{"key":"60080988726e9-30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2019.100370"},{"key":"60080988726e9-31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.12.011"},{"key":"60080988726e9-32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2010.09.019"},{"key":"60080988726e9-33","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp205"},{"key":"60080988726e9-34","doi-asserted-by":"publisher","DOI":"10.4137\/CMC.S17068"},{"key":"60080988726e9-35","doi-asserted-by":"publisher","DOI":"10.1177\/2047487318814298"},{"key":"60080988726e9-36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2019.109779"},{"key":"60080988726e9-37","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00073-X"},{"key":"60080988726e9-38","doi-asserted-by":"publisher","DOI":"10.1177\/000331970405500407"},{"key":"60080988726e9-39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2010.02360.x"},{"key":"60080988726e9-40","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.65.7.1299"},{"key":"60080988726e9-41","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.12.035"},{"key":"60080988726e9-42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.03.055"},{"key":"60080988726e9-43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.09.016"},{"key":"60080988726e9-44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.11.015"},{"key":"60080988726e9-45","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000227"},{"key":"60080988726e9-46","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(92)90917-K"},{"key":"60080988726e9-47","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-016-0579-9"},{"key":"60080988726e9-48","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.834739"},{"key":"60080988726e9-49","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv100"},{"key":"60080988726e9-50","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.172528"},{"key":"60080988726e9-51","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.3.518"},{"key":"60080988726e9-52","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00458.2015"},{"key":"60080988726e9-53","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(97)02953-7"},{"key":"60080988726e9-54","first-page":"2565","article-title":"International standardization of diagnostic criteria for vasospastic\nangina.","volume":"38","author":"Beltrame JF","year":"2017","journal-title":"Eur Heart J"},{"key":"60080988726e9-55","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-013-0615-9"},{"key":"60080988726e9-56","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.037283"},{"key":"60080988726e9-57","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197906143002402"},{"key":"60080988726e9-58","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht296"},{"key":"60080988726e9-59","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000097116.29625.7C"},{"key":"60080988726e9-60","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.12.084"},{"key":"60080988726e9-61","doi-asserted-by":"publisher","DOI":"10.4037\/ajcc2008.17.1.14"},{"key":"60080988726e9-62","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1093\/eurheartj\/ehy806","article-title":"Prediction of obstructive coronary artery disease and prognosis in patients with suspected stable angina.","volume":"40","author":"Reeh J","year":"2019","journal-title":"Eur Heart J"},{"key":"60080988726e9-63","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000154568.43333.82"},{"key":"60080988726e9-64","doi-asserted-by":"publisher","DOI":"10.1080\/03630242.2019.1643817"},{"key":"60080988726e9-65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2013.06.001"},{"key":"60080988726e9-66","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.10.052"},{"key":"60080988726e9-67","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.609990"},{"key":"60080988726e9-68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093170"},{"key":"60080988726e9-69","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.726562"},{"key":"60080988726e9-70","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.02.074"},{"key":"60080988726e9-71","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.50"},{"key":"60080988726e9-72","first-page":"S21","article-title":"Insights from the NHLBI-Sponsored Women\u2019s Ischemia\nSyndrome Evaluation (WISE) study: part II: gender differences in presentation,\ndiagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis\nand macrovascular and microvascular coronary disease.","volume":"47","author":"Bairey Merz CN","year":"2006","journal-title":"2006"},{"key":"60080988726e9-73","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy185"},{"key":"60080988726e9-74","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl040"},{"key":"60080988726e9-75","first-page":"881","article-title":"Angina-linked syncope and lack of calcium antagonist therapy predict cardiac arrest before definitive diagnosis of vasospastic angina.","volume":"5","author":"Igarashi Y","year":"1994","journal-title":"Coron Artery Dis"},{"key":"60080988726e9-76","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-199302000-00008"},{"key":"60080988726e9-77","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.06.016"},{"key":"60080988726e9-78","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.114.002481"},{"key":"60080988726e9-79","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(93)90148-6"},{"key":"60080988726e9-80","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012369"},{"key":"60080988726e9-81","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.006194"},{"key":"60080988726e9-82","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-008-0220-3"},{"key":"60080988726e9-83","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.09.006"},{"key":"60080988726e9-84","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.01.157"},{"key":"60080988726e9-85","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00982"},{"key":"60080988726e9-86","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2019-315042"},{"key":"60080988726e9-87","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.02.009"},{"key":"60080988726e9-88","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000017199.09457.3D"},{"key":"60080988726e9-89","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2003.11.009"},{"key":"60080988726e9-90","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.07.011"},{"key":"60080988726e9-91","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.12.053"},{"key":"60080988726e9-92","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-17-00449"},{"key":"60080988726e9-93","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.11.040"},{"key":"60080988726e9-94","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.113.001049"},{"key":"60080988726e9-95","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000080700.98607.D1"},{"key":"60080988726e9-96","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005361"},{"key":"60080988726e9-97","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.04.077"},{"key":"60080988726e9-98","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2017.09.012"},{"key":"60080988726e9-99","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy394"},{"key":"60080988726e9-100","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.10.066"},{"key":"60080988726e9-101","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.037021"},{"key":"60080988726e9-102","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198610233151702"},{"key":"60080988726e9-103","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90449-4"},{"key":"60080988726e9-104","doi-asserted-by":"publisher","DOI":"10.3791\/54295"},{"key":"60080988726e9-105","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2012-302042"},{"key":"60080988726e9-106","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx667"},{"key":"60080988726e9-107","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.024534"},{"key":"60080988726e9-108","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.01.023"},{"key":"60080988726e9-109","doi-asserted-by":"publisher","DOI":"10.5539\/gjhs.v4n1p65"},{"key":"60080988726e9-110","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-311155"},{"key":"60080988726e9-111","doi-asserted-by":"publisher","DOI":"10.1111\/micc.12430"},{"key":"60080988726e9-112","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000115525.92645.16"},{"key":"60080988726e9-113","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw106"},{"key":"60080988726e9-114","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy339"},{"key":"60080988726e9-115","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2011.07.011"},{"key":"60080988726e9-116","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcvp\/pvu020"},{"key":"60080988726e9-117","doi-asserted-by":"publisher","DOI":"10.15420\/icr.2019.04.R1"},{"key":"60080988726e9-118","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.773747"},{"key":"60080988726e9-119","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.03.018"},{"key":"60080988726e9-120","doi-asserted-by":"publisher","DOI":"10.1097\/MCA.0000000000000054"},{"key":"60080988726e9-121","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw021"},{"key":"60080988726e9-122","doi-asserted-by":"publisher","DOI":"10.1007\/s10557-013-6439-z"},{"key":"60080988726e9-123","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.031373"},{"key":"60080988726e9-124","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328340a08e"},{"key":"60080988726e9-125","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.11.001"},{"key":"60080988726e9-126","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-010-0083-8"},{"key":"60080988726e9-127","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.06.008"},{"key":"60080988726e9-128","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.12.055"},{"key":"60080988726e9-129","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv647"},{"key":"60080988726e9-130","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2018.7019"},{"key":"60080988726e9-131","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2010.11.035"},{"key":"60080988726e9-132","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.02.045"},{"key":"60080988726e9-133","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.306532"},{"key":"60080988726e9-134","doi-asserted-by":"publisher","DOI":"10.2310\/6650.2005.00205.70"},{"key":"60080988726e9-135","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.08.876"},{"key":"60080988726e9-136","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2019.11.015"}],"container-title":["EuroIntervention"],"original-title":[],"deposited":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T10:46:06Z","timestamp":1611139566000},"score":1,"resource":{"primary":{"URL":"https:\/\/eurointervention.pcronline.com\/doi\/10.4244\/EIJY20M07_01"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":137,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["EIJY20M07_01"],"URL":"https:\/\/doi.org\/10.4244\/eijy20m07_01","relation":{},"ISSN":["1774-024X"],"issn-type":[{"value":"1774-024X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}