{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:35:56Z","timestamp":1770269756529,"version":"3.49.0"},"reference-count":67,"publisher":"Baishideng Publishing Group Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastrointest Oncol"],"abstract":"<jats:p>Colorectal cancer (CRC) is the most prevalent cancer globally, and its traditional treatment modalities commonly encompass radiation therapy, chemotherapy, surgery and the administration of cytotoxic drugs. Currently, novel chemotherapy drugs that combine traditional Chinese medicine (TCM) with herbal extracts exhibit superior comprehensive benefits. Herein, we delved into an article authored by Wang et al , focusing specifically on the pharmacological effects of \"Herba Patriniae   and Coix  seed (HC)\" and their targeted mechanisms in combating CRC. From the perspective of TCM philosophy, damp-heat stagnation and toxicity are the cardinal pathogenic factors underlying CRC. HC, renowned for their abilities to antipyretic and enhance diuresis, have demonstrated promising efficacy in preliminary studies for the treatment of CRC. These findings offer potential insights in favor of fostering anti-cancer medications.<\/jats:p>","DOI":"10.4251\/wjgo.v17.i3.99673","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T09:40:22Z","timestamp":1739439622000},"source":"Crossref","is-referenced-by-count":2,"title":["Pharmacological role of <i>Herba Patriniae<\/i> and <i>Coix<\/i> seed in colorectal cancer"],"prefix":"10.4251","volume":"17","author":[{"given":"Yu-Xin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guan-Yue","family":"Shan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Ya","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ying","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Na","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,3,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-21-1059"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3390\/nu14010123"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.961653"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v16.i8.3539"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2018.12.019"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.7150\/jca.5829"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v112.agast970594"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3970-5"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxz268"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1242458"},{"key":"B12","unstructured":"World Cancer Research Fund.   Diet, Nutrition, Physical Activity and Colorectal Cancer. 2018"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1023\/a:1008999232442"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31046"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/21.3.361"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0724"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-019-0685-7"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.37341"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33945"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.5072"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2008.839"},{"key":"B22","unstructured":"Drope J, Schluger NW.   The Tobacco Atlas. 6th ed. Atlanta: American Cancer Society, 2018"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0000000000000011"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01851-y"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-009-0518-4"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.3390\/cells13141221"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.7150\/thno.29271"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2017-204739"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3967"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-020-09915-5"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz276.029"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.joim.2020.07.005"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1120672"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1007\/s11655-007-0156-z"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1129874"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.117309"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113264"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.19540\/j.cnki.cjcmm.20170707.001"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-19-019"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-020-00596-9"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2021.110717"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/s2225-4110(16)30112-2"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.3892\/or.2016.4958"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.529962"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000021619"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.3892\/or.2013.2528"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0080-4"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-018-0980-3"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-021-06458-y"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.3390\/foods10112833"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-022-07371-8"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115690"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26196032"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-019-0110-x"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2022.100909"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.151"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1186\/1756-9966-27-31"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.142"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25040894"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113388"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2018.08.005"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2016.48"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.154900"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-019-0361-4"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2022.01.009"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00762-6"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-021-03301-6"}],"container-title":["World Journal of Gastrointestinal Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-5204\/full\/v17\/i3\/99673.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-5204\/full\/v17\/i3\/99673.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T09:41:00Z","timestamp":1739439660000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-5204\/full\/v17\/i3\/99673.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,15]]},"references-count":67,"journal-issue":{"issue":"3"},"alternative-id":["99673"],"URL":"https:\/\/doi.org\/10.4251\/wjgo.v17.i3.99673","relation":{},"ISSN":["1948-5204"],"issn-type":[{"value":"1948-5204","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,15]]}}}