{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T15:57:05Z","timestamp":1774540625087,"version":"3.50.1"},"reference-count":21,"publisher":"Baishideng Publishing Group Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastrointest Endosc"],"abstract":"BACKGROUND<\/jats:p>\n Duodenal Brunner's gland hyperplasia (BGH) is a therapeutic target when complications such as bleeding or gastrointestinal obstruction occur or when malignancy cannot be ruled out. Herein, we present a case of large BGH treated with endoscopic mucosal resection (EMR).<\/jats:p>\n CASE SUMMARY<\/jats:p>\n An 83-year-old woman presented at our hospital with dizziness. Blood tests revealed severe anemia, esophagogastroduodenoscopy showed a 6.5 cm lesion protruding from the anterior wall of the duodenal bulb, and biopsy revealed the presence of glandular epithelium. Endoscopic ultrasonography (EUS) demonstrated relatively high echogenicity with a cystic component. The muscularis propria was slightly elevated at the base of the lesion. EMR was performed without complications. The formalin-fixed lesion size was 6 cm \u00d7 3.5 cm \u00d7 3 cm, showing nodular proliferation of non-dysplastic Brunner's glands compartmentalized by fibrous septa, confirming the diagnosis of BGH. Reports of EMR or hot snare polypectomy are rare for duodenal BGH > 6 cm. In this case, the choice of EMR was made by obtaining information on the base of the lesion as well as on the internal characteristics through EUS.<\/jats:p>\n CONCLUSION<\/jats:p>\n Large duodenal lesions with good endoscopic maneuverability and no evident muscular layer involvement on EUS may be resectable via EMR.<\/jats:p>","DOI":"10.4253\/wjge.v16.i6.368","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T04:19:53Z","timestamp":1718338793000},"page":"368-375","source":"Crossref","is-referenced-by-count":4,"title":["Giant Brunner's gland hyperplasia of the duodenum successfully resected en bloc<\/i> by endoscopic mucosal resection: A case report"],"prefix":"10.4253","volume":"16","author":[{"given":"Makomo","family":"Makazu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chikamasa","family":"Ichita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chihiro","family":"Sumida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miki","family":"Nagayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Teshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,6,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2018-0034-RA"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.05.0564"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2022.107747"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i35.12501"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2009.24.2.101"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.01.032"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1111\/den.13269"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/den.13367"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-35849"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2020.259"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8861308"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-021-08740-3"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1159\/000531231"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1159\/000452363"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2001.112041"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1155\/2006\/806926"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.11.025"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-9039-3"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajg.2018.08.004"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1159\/000490098"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-019-1074-1"}],"container-title":["World Journal of Gastrointestinal Endoscopy"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-5190\/full\/v16\/i6\/368.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-5190\/full\/v16\/i6\/368.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T04:20:36Z","timestamp":1718338836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-5190\/full\/v16\/i6\/368.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,16]]},"references-count":21,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4253\/wjge.v16.i6.368","relation":{},"ISSN":["1948-5190"],"issn-type":[{"value":"1948-5190","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,16]]}}}