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However, evidence regarding the capability of EUS-GBD to normalize total bilirubin in patients with DMBO is still lacking. Notably, bilirubin normalization is regarded as mandatory before starting chemotherapy, thus representing a crucial outcome of any biliary drainage method for DMBO. Our study aimed to summarize and discuss the current evidence concerning the effectiveness of EUS-GBD for bilirubin normalization in DMBO.<\/jats:p>","DOI":"10.4253\/wjge.v18.i2.114771","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T02:06:53Z","timestamp":1770170813000},"source":"Crossref","is-referenced-by-count":4,"title":["Endoscopic ultrasound-guided gallbladder drainage for bilirubin normalization in distal malignant biliary obstruction: A focused review"],"prefix":"10.4253","volume":"18","author":[{"given":"Alberto","family":"Martino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Granata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco 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