{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:30:05Z","timestamp":1793827805388,"version":"4.6.1"},"reference-count":68,"publisher":"Baishideng Publishing Group Inc.","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJH"],"published-print":{"date-parts":[[2019,8,27]]},"DOI":"10.4254\/wjh.v11.i8.619","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T07:31:48Z","timestamp":1566545508000},"page":"619-637","source":"Crossref","is-referenced-by-count":182,"title":["Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice"],"prefix":"10.4254","volume":"11","author":[{"given":"Kandy T","family":"Vel\u00e1zquez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reilly T","family":"Enos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jackie E","family":"Bader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander T","family":"Sougiannis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith S","family":"Carson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioulia","family":"Chatzistamou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A","family":"Carson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Nagarkatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitzi","family":"Nagarkatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E Angela","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28123"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i45.16841"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.04.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2007.00329.x"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Wareham NJ, van Sluijs EM, Ekelund U. Physical activity and obesity prevention: a review of the current evidence. Proc Nutr Soc 2005; 64: 229-247","DOI":"10.1079\/PNS2005423"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.080708.082713"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2008.00468.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00291.2013"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/nature07540"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-300705"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009085"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/nature11450"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004559"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26093"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2017.72"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-312729"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.02.015"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062885"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28356"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Koopman R, Schaart G, Hesselink MK. Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids. Histochem Cell Biol 2001; 116: 63-68","DOI":"10.1007\/s004180100297"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00207.2016"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks808"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i7.1768"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00183.2014"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-nutr-071811-150644"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1126\/science.1208344"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2016.1270811"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-013-0404-6"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114515002093"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-303816"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1177\/019262339502300504"},{"key":"ref32","unstructured":"Itagaki H, Shimizu K, Morikawa S, Ogawa K, Ezaki T. Morphological and functional characterization of non-alcoholic fatty liver disease induced by a methionine-choline-deficient diet in C57BL\/6 mice. Int J Clin Exp Pathol 2013; 6: 2683-2696"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127991"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1080\/15384047.2018.1537574"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13412"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M030700"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.080703"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp236"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00079.2013"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00476.2011"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v8.i16.673"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2009.00386.x"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-10-49"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50316"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01774.x"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2006.02.011"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.2337\/db07-0156"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00074.2008"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1556\/EUJMI-D-14-00035"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02795"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1159\/000440905"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.04.011"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1096\/fj.03-0771fje"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2013.06.005"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.543215"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1186\/s12986-017-0202-6"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i34.7727"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20160"},{"key":"ref59","doi-asserted-by":"crossref","unstructured":"Bargiggia S, Maconi G, Elli M, Molteni P, Ardizzone S, Parente F, Todaro I, Greco S, Manzionna G, Bianchi Porro G. Sonographic prevalence of liver steatosis and biliary tract stones in patients with inflammatory bowel disease: study of 511 subjects at a single center. J Clin Gastroenterol 2003; 36: 417-420","DOI":"10.1097\/00004836-200305000-00012"},{"key":"ref60","unstructured":"Riegler G, D'Inc\u00e0 R, Sturniolo GC, Corrao G, Del Vecchio Blanco C, Di Leo V, Carrat\u00f9 R, Ingrosso M, Pelli MA, Morini S, Valpiani D, Cantarini D, Usai P, Papi C, Caprilli R. Hepatobiliary alterations in patients with inflammatory bowel disease: a multicenter study. Caprilli amp; Gruppo Italiano Studio Colon-Retto. Scand J Gastroenterol 1998; 33: 93-98"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000832"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1038\/srep08096"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-19753-9"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26319"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28572"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1038\/nutd.2015.9"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151829"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2016.62150"}],"container-title":["World Journal of Hepatology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v11\/i8\/619.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,17]],"date-time":"2021-01-17T08:02:15Z","timestamp":1610870535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v11\/i8\/619.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,27]]},"references-count":68,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8,27]]}},"URL":"https:\/\/doi.org\/10.4254\/wjh.v11.i8.619","relation":{},"ISSN":["1948-5182"],"issn-type":[{"value":"1948-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8,27]]}}}