{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:36:04Z","timestamp":1791387364238,"version":"4.3.3"},"reference-count":25,"publisher":"Baishideng Publishing Group Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Hepatol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n                  <jats:p>Non-alcoholic fatty liver disease (NAFLD) management requires sustainable lifestyle modifications. This study aimed to evaluate the effectiveness of the RESET care plan, a comprehensive program that is an integrated personalized diet, exercise, and cognitive behavior therapy, delivered via  MyTatva\u2019s digital health application enabled through a body composition analyzer (BCA) and smartwatch.<\/jats:p>\n                  <jats:p>AIM<\/jats:p>\n                  <jats:p>To evaluates the effectiveness of the comprehensive program delivered via  MyTatva\u2019s digital health app enabled through internet of thing devices.<\/jats:p>\n                  <jats:p>METHODS<\/jats:p>\n                  <jats:p>This retrospective observational study analyzed deidentified data from 22 participants enrolled in the MyTatva RESET care program. Participants were divided into three groups: Group A, diet plan; Group B, diet + exercise plan; and Group C, diet + exercise + cognitive behavioral therapy plan. Participants were provided with a BCA and smartwatch for continuous monitoring of anthropometric parameters. Statistical analysis, including one-way ANOVA and post-hoc Tukey\u2019s Honest Significant Difference test, was conducted to compare mean changes in anthropometric parameters across the groups.<\/jats:p>\n                  <jats:p>RESULTS<\/jats:p>\n                  <jats:p>All intervention groups showed significant improvement across all anthropometric parameters. Group C showed the most significant improvements, with mean weight reduction of 7% or more (6.99 \u00b1 2.98 kg, 7.00% \u00b1 3.39%; P  = 0.002) from baseline, a benchmark associated with improved NAFLD conditions. Post-hoc analysis revealed that Group C had significantly greater improvements than Groups A and B. Weight reduction was observed in 85.7% of Group A participants, 77.8% of Group B participants, and 100% of Group C participants.<\/jats:p>\n                  <jats:p>CONCLUSION<\/jats:p>\n                  <jats:p>The comprehensive RESET care plan achieved a 7% weight reduction in 12 weeks, demonstrating its effectiveness in managing NAFLD. These results support adopting digitally supported, patient-centric approaches for NAFLD treatment.<\/jats:p>","DOI":"10.4254\/wjh.v17.i1.101630","type":"journal-article","created":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T20:52:25Z","timestamp":1736110345000},"source":"Crossref","is-referenced-by-count":5,"title":["Effectiveness of RESET care program: A real-world-evidence on managing non-alcoholic fatty liver disease through digital health interventions"],"prefix":"10.4254","volume":"17","author":[{"given":"Jayesh","family":"Soni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhilesh","family":"Pathak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir","family":"Gharia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devina","family":"Aswal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaymin","family":"Parikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prachi","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astha","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhvni","family":"Lalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Twinkle","family":"Maheshwari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2020.0067"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-022-00980-1"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3390\/livers3030033"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-3444"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-016-4153-y"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-023-01918-w"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-017-0304-7"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcd.2010.02.004"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.2337\/dsi23-0009"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.14309\/ctg.0000000000000575"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.2196\/30239"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.20944\/preprints202401.2153.v1"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-021-00827-0"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.597583"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1186\/s12937-020-00580-6"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3390\/diseases5040023"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1081096"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3390\/nu15102266"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2018.1503947"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.01.015"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3727\/105221617X15124844266408"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.08.011"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3390\/nu14112223"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.254"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i29.10128"}],"container-title":["World Journal of Hepatology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v17\/i1\/101630.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v17\/i1\/101630.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T20:53:35Z","timestamp":1736110415000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v17\/i1\/101630.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,27]]},"references-count":25,"journal-issue":{"issue":"1"},"alternative-id":["101630"],"URL":"https:\/\/doi.org\/10.4254\/wjh.v17.i1.101630","relation":{},"ISSN":["1948-5182"],"issn-type":[{"value":"1948-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,27]]}}}