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In Eastern Ethiopia, HBV-infected patients with cirrhosis were found to be positive for the HBV e antigen and to have a higher viral load than those without cirrhosis. Notably, 54.4% of patients practiced khat chewing and 18.1% consumed excessive amounts of alcohol. Tenofovir disoproxil fumarate effectively suppressed HBV DNA in those infected with HBV. It is important to elucidate the actual status of HBV infection in Eastern Ethiopia to eliminate HBV infection worldwide by 2030. HBV vaccination and the educational programs for Health Science students that provide practical strategies could help to reduce HBV infection in Eastern Ethiopia.<\/jats:p>","DOI":"10.4254\/wjh.v17.i1.99209","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T01:52:25Z","timestamp":1736128345000},"source":"Crossref","is-referenced-by-count":3,"title":["Hepatitis B virus infection and its treatment in Eastern Ethiopia"],"prefix":"10.4254","volume":"17","author":[{"given":"Tatsuo","family":"Kanda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reina","family":"Sasaki-Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsunori","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Terai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-015-9675-4"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000842"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3390\/diseases6010003"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v16.i7.995"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(23)00197-8"},{"key":"B6","unstructured":"Hepatitis B Foundation.   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