{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:20:20Z","timestamp":1792592420294,"version":"4.5.0"},"reference-count":22,"publisher":"Baishideng Publishing Group Inc.","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Hepatol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>The hepatosplenic schistosomiasis (HSS) with portal hypertension can cause vascular complications such as hepatopulmonary syndrome (HPS). HPS increases the risk of mortality in patients with cirrhosis; however, there is no data on the mortality of patients with HSS and HPS.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To perform a survival analysis of patients with HPS related to cirrhotic and non-cirrhotic (schistosomiasis) portal hypertension.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>From August 2023 to January 2024, medical records and the official mortality information service of 121 patients who participated in a cross-sectional study on HPS between 2010 and 2012 were analyzed. Survival curves were created using the Kaplan-Meier method, and comparisons were performed using the log-rank test. Cox regression models estimated the hazard ratios (HR).<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>Overall, data of 113 patients were analyzed; most (55.8%) had HSS and concomitant cirrhosis (HSS\/cirrhosis). Meanwhile, HPS was present in 39 (34.5%) patients. Death occurred in 65 patients [57.5%; 95% confidence interval (CI): 48%-67%. The average time to death was lower in those with HPS when compared to those without HPS (3.37 years vs  5.65 years; P  = 0.017). According to the cause of liver disease, patients with HSS\/cirrhosis died earlier, and their risk of death was twice as high compared with patients with HSS without cirrhosis (HR: 2.17; 95%CI: 1.3-3.60; P  = 0.003). Meanwhile, there were no differences when comparing the two groups with and without HPS (HR: 1.01; 95%CI: 0.59-1.73; P  = 0.967).<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Patients with HSS and concomitant cirrhosis had a lower survival rate, but there was no difference in survival regardless of the presence of HPS.<\/jats:p>","DOI":"10.4254\/wjh.v17.i2.99134","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:51:46Z","timestamp":1740012706000},"source":"Crossref","is-referenced-by-count":3,"title":["Survival of patients with hepatopulmonary syndrome related to cirrhotic and non-cirrhotic (schistosomiasis) portal hypertension"],"prefix":"10.4254","volume":"17","author":[{"given":"Melissa M","family":"Rolim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liana G","family":"Farsoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos F","family":"Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brivaldo","family":"Markman-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo","family":"Querette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmundo P","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L","family":"Domingues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"B1","unstructured":"World Health Organization.   Status of schistosomiasis endemic countries: 2023. [cited 14 July 2024]. Available from: https:\/\/apps.who.int\/neglected_diseases\/ntddata\/sch\/sch.html?geog=0&indicator=i0&date=2022&bbox=234.07835000000003,62.897000000000006,234.07835000000003,90.59700000000002&printmode=true"},{"key":"B2","unstructured":"Minist\u00e9rio da Sa\u00fade.   Monitoramento dos casos de arboviroses at\u00e9 a semana epidemiol\u00f3gica 45 de 2022. [cited 14 July 2024]. Avaliable from: https:\/\/www.gov.br\/saude\/pt-br\/centrais-de-conteudo\/publicacoes\/boletins\/epidemiologicos\/edicoes\/2022\/boletim-epidemiologico-vol-53-no43\/view"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.635513"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed8030145"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10102022"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.2147\/HMER.S155962"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s11901-023-00612-9"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v10.i17.5531"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2023.03.008"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00010904"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.08.013"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2022.100527"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-022-01284-x"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.09.050"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2022.04.021"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.06.038"},{"key":"B17","unstructured":"Cox DR, Ookes D.   Analysis of survival. 1st ed. New York: Chapman and Hall\/CRC, 1984: 91-104"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.26633\/RPSP.2023.146"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmer.2021.100852"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12713"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02304-2021"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/S1665-2681(19)31275-X"}],"container-title":["World Journal of Hepatology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v17\/i2\/99134.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v17\/i2\/99134.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T00:52:15Z","timestamp":1740012735000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1948-5182\/full\/v17\/i2\/99134.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,27]]},"references-count":22,"journal-issue":{"issue":"2"},"alternative-id":["99134"],"URL":"https:\/\/doi.org\/10.4254\/wjh.v17.i2.99134","relation":{},"ISSN":["1948-5182"],"issn-type":[{"value":"1948-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,27]]}}}