{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:59:21Z","timestamp":1789624761064,"version":"build-2803163510"},"reference-count":74,"publisher":"Baishideng Publishing Group Inc.","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJH"],"published-print":{"date-parts":[[2014]]},"DOI":"10.4254\/wjh.v6.i10.688","type":"journal-article","created":{"date-parts":[[2014,10,25]],"date-time":"2014-10-25T02:29:38Z","timestamp":1414204178000},"page":"688","source":"Crossref","is-referenced-by-count":22,"title":["Severe alcoholic hepatitis-current concepts, diagnosis and treatment options"],"prefix":"10.4254","volume":"6","author":[{"given":"Won","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.34734"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0805786"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Mathurin P, Duchatelle V, Ramond MJ, Degott C, Bedossa P, Erlinger S, Benhamou JP, Chaput JC, Rueff B, Poynard T. Survival and prognostic factors in patients with severe alcoholic hepatitis treated with prednisolone. Gastroenterology 1996;110:1847-1853.","DOI":"10.1053\/gast.1996.v110.pm8964410"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3181fdef1d"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.02104.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20503"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.050781"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0100870"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21607"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Maddrey WC, Boitnott JK, Bedine MS, Weber FL, Mezey E, White RI. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology 1978;75:193-199.","DOI":"10.1016\/0016-5085(78)90401-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1040605"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i44.7825"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1185\/030079905x56493"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2012.04.004"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23258"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26185"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21930"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.12.056"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-008-9106-x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.189639"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/cc10424"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0910102"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24109"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23500"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Carithers RL, Herlong HF, Diehl AM, Shaw EW, Combes B, Fallon HJ, Maddrey WC. Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. Ann Intern Med 1989;110:685-690.","DOI":"10.7326\/0003-4819-110-9-685"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.224097"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27211"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24159"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.hep.2003.09.038"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.01.018"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2004.11.001"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12427"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(07)61814-5"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Mendenhall CL, Moritz TE, Roselle GA, Morgan TR, Nemchausky BA, Tamburro CH, Schiff ER, McClain CJ, Marsano LS, Allen JI. Protein energy malnutrition in severe alcoholic hepatitis: diagnosis and response to treatment. The VA Cooperative Study Group #275. JPEN J Parenter Enteral Nutr 1995;19:258-265.","DOI":"10.1177\/0148607195019004258"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.8627"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.04.062"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26748"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology 2000;119:1637-1648.","DOI":"10.1053\/gast.2000.20189"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12279"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007339.pub2"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.05.014"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.276300"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.276301"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-14-262"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.10.010"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1101214"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20206"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.08.057"},{"key":"ref49","doi-asserted-by":"crossref","unstructured":"Akerman P, Cote P, Yang SQ, McClain C, Nelson S, Bagby GJ, Diehl AM. Antibodies to tumor necrosis factor-alpha inhibit liver regeneration after partial hepatectomy. Am J Physiol 1992;263:G579-G585.","DOI":"10.1152\/ajpgi.1992.263.4.G579"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Strieter RM, Kunkel SL, Bone RC. Role of tumor necrosis factor-alpha in disease states and inflammation. Crit Care Med 1993;21:S447-S463.","DOI":"10.1097\/00003246-199310001-00006"},{"key":"ref51","doi-asserted-by":"crossref","unstructured":"Yamada Y, Kirillova I, Peschon JJ, Fausto N. Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc Natl Acad Sci USA 1997;94:1441-1446.","DOI":"10.1073\/pnas.94.4.1441"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21278"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105703"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.06.013"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1172\/jci60777"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22470"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2013.10.008"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2013.10.018"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.07003.x"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2010.01398.x"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.09.008"},{"key":"ref62","doi-asserted-by":"crossref","unstructured":"Bjarnason I, Peters TJ, Wise RJ. The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet 1984;1:179-182.","DOI":"10.1016\/S0140-6736(84)92109-3"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.11.027"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.154"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22317"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.05.018"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.05.042"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00350.2009"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2008.08.006"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1097\/mog.0000000000000065"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.2147\/jir.s35227"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.083188"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23837"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12032"}],"container-title":["World Journal of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1948-5182\/full\/v6\/i10\/688.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,16]],"date-time":"2019-08-16T12:49:12Z","timestamp":1565959752000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1948-5182\/full\/v6\/i10\/688.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":74,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.4254\/wjh.v6.i10.688","relation":{},"ISSN":["1948-5182"],"issn-type":[{"value":"1948-5182","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}