{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T03:44:13Z","timestamp":1781063053784,"version":"3.54.1"},"reference-count":10,"publisher":"The Korean Society of Critical Care Medicine","issue":"4","license":[{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["accjournal.org"],"crossmark-restriction":true},"short-container-title":["ACC"],"published-print":{"date-parts":[[2023,11,30]]},"abstract":"<jats:p>Myoclonic status epilepticus (MSE) is a sign of severe neurologic injury in cardiac arrest patients. To our knowledge, MSE has not been described as a result of prolonged hyperpyrexia. A 56-yearold man with coronavirus disease 2019 presented with acute respiratory distress syndrome, septic\/hypovolemic shock, and presumed community-acquired pneumonia. Five days after presentation, he developed a sustained fever of 42.1\u00b0C that did not respond to acetaminophen or ice water gastric lavage. After several hours, he was placed on surface cooling. Three hours after fever resolution, new multifocal myoclonus was noted in the patient\u2019s arms and trunk. Electroencephalography showed midline spikes consistent with MSE, which resolved with 40 mg\/kg of levetiracetam. This case demonstrates that severe hyperthermia can cause cortical injury significant enough to trigger MSE and should be treated emergently using the most aggressive measures available. Providers should have a low threshold for electroencephalography in intubated patients with a recent history of hyperpyrexia. <\/jats:p>","DOI":"10.4266\/acc.2021.01452","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T23:14:49Z","timestamp":1648163689000},"page":"509-512","update-policy":"https:\/\/doi.org\/10.4266\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Myoclonic status epilepticus after severe hyperthermia in a patient with coronavirus disease 2019"],"prefix":"10.4266","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5712-7238","authenticated-orcid":true,"given":"Katherine A","family":"Hill","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4574-368X","authenticated-orcid":true,"given":"John J","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0796-2272","authenticated-orcid":true,"given":"Sara M","family":"Schaefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2790","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350219"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000086755"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520310099023"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebcr.2012.10.003"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2020.08.022"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-016-1376-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0079-6123(06)62017-7"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1080\/09629359791839"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199708000-00017"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.npbr.2020.10.001"}],"container-title":["Acute and Critical Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/accjournal.org\/upload\/pdf\/acc-2021-01452.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/accjournal.org\/journal\/view.php?doi=10.4266\/acc.2021.01452","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/accjournal.org\/upload\/pdf\/acc-2021-01452.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T06:47:35Z","timestamp":1701326855000},"score":1,"resource":{"primary":{"URL":"http:\/\/accjournal.org\/journal\/view.php?doi=10.4266\/acc.2021.01452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,30]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,11]]}},"URL":"https:\/\/doi.org\/10.4266\/acc.2021.01452","relation":{},"ISSN":["2586-6052","2586-6060"],"issn-type":[{"value":"2586-6052","type":"print"},{"value":"2586-6060","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,30]]},"assertion":[{"value":"2021-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-24","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}