{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:47:06Z","timestamp":1778500026739,"version":"3.51.4"},"reference-count":32,"publisher":"The Korean Society of Critical Care Medicine","issue":"1","license":[{"start":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T00:00:00Z","timestamp":1677456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/100016275","name":"Seoul National University Bundang Hospital","doi-asserted-by":"publisher","award":["02-2020-0034"],"award-info":[{"award-number":["02-2020-0034"]}],"id":[{"id":"10.13039\/100016275","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["accjournal.org"],"crossmark-restriction":true},"short-container-title":["ACC"],"published-print":{"date-parts":[[2023,2,28]]},"abstract":"<jats:p>Background: There are conflicting results regarding the association between body mass index and the prognosis of cardiac arrest patients. We investigated the association of the composition and distribution of muscle and fat with neurologic outcomes at hospital discharge in successfully resuscitated out-of-hospital cardiac arrest (OHCA) patients.Methods: This prospective, single-centre, observational study involved adult OHCA patients, conducted between April 2019 and June 2021. The ratio of total skeletal muscle, upper limb muscle, lower limb muscle, and total fat to body weight was measured using InBody S10, a bioimpedance analyser, after achieving the return of spontaneous circulation. Restricted cubic spline curves with four knots were used to examine the relationship between total skeletal muscle, upper limb muscle, and lower limb muscle relative to total body weight and neurologic outcome at discharge. Multivariable logistic regression analysis was performed to assess an independent association.Results: A total of 66 patients were enrolled in the study. The proportion of total muscle and lower limb muscle positively correlated with the possibility of having a good neurologic outcome. The proportion of lower limb muscle showed an independent association in the multivariable analysis (adjusted odds ratio, 2.29; 95% confidence interval, 1.06\u201313.98), and its optimal cut-off value calculated through receiver operating characteristic curve analysis was 23.1%, which can predict a good neurological outcome. Conclusions: A higher proportion of lower limb muscle to body weight was independently associated with the probability of having a good neurologic outcome in OHCA patients.<\/jats:p>","DOI":"10.4266\/acc.2022.01389","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T06:07:16Z","timestamp":1677478036000},"page":"104-112","update-policy":"https:\/\/doi.org\/10.4266\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Lower limb muscle matters in patients with hypoxic brain injury following out-of-hospital cardiac arrest"],"prefix":"10.4266","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0277-0987","authenticated-orcid":true,"given":"Dong-Hyun","family":"Jang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3594-8403","authenticated-orcid":true,"given":"Seung Min","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0490-1837","authenticated-orcid":true,"given":"Dong Keon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3911-8888","authenticated-orcid":true,"given":"Dong Won","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9469-8977","authenticated-orcid":true,"given":"Chang Woo","family":"Im","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3594-8403","authenticated-orcid":true,"given":"You Hwan","family":"Jo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4747-9250","authenticated-orcid":true,"given":"Kui Ja","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2790","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2020.02.044"},{"key":"ref2","first-page":"350","volume-title":"Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication: a Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke","author":"Nolan","year":"2008"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1670-9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-031655"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2016.09.011"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.06.019"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2018.03.079"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-021-00837-x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0265656"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2022.03.032"},{"key":"ref11","first-page":"S444","volume-title":"Part 7: adult advanced cardiovascular life support: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care","author":"Link","year":"2015"},{"key":"ref12","first-page":"S366","volume-title":"Part 3: adult basic and advanced life support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care","author":"Panchal","year":"2020"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3390\/nu10060738"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2011.04.001"},{"key":"ref15","first-page":"1286","volume-title":"Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia); 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