{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:24:15Z","timestamp":1777505055012,"version":"3.51.4"},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,5,1]]},"abstract":"<jats:p>We investigated the humoral immune response against different species of <jats:italic>Rickettsia<\/jats:italic> in serum samples from small rodents collected in two areas of a silent focus for Brazilian spotted fever in the eastern region of Minas Gerais State, Brazil. Sera samples were analyzed by indirect immunofluorescence assay using antigens from <jats:italic>Rickettsia<\/jats:italic> species of the spotted fever, ancestral, and transition groups. Titers \u2265 1:64 were considered positive. In Santa Cruz do Escalvado, 94% (30 of 32) of the samples collected from <jats:italic>Rattus rattus<\/jats:italic>, 22% (5 of 23) from <jats:italic>Nectomys squamipes<\/jats:italic>, and 80% (4 of 5) from <jats:italic>Akodon<\/jats:italic> sp., reacted by indirect immunofluorescence assay with <jats:italic>Rickettsia<\/jats:italic> antigens of the spotted fever group. In the municipality of Pingo D'\u00c1gua, 84% (26 of 31) of the samples collected from <jats:italic>R. rattus<\/jats:italic>, 86% (6 of 7) of the samples from <jats:italic>Oryzomys subflavus<\/jats:italic>, 86% (6 of 7) from <jats:italic>N. squamipes<\/jats:italic>, and 100% (1 of 1) from <jats:italic>Bolomys<\/jats:italic> sp. contained antibodies that reacted with rickettsial antigens of the spotted fever group. These results demonstrated the previous exposure of small rodents to spotted fever group <jats:italic>Rickettsia<\/jats:italic>, suggesting the participation of these animals in the natural history of these rickettsiae in this region.<\/jats:p>","DOI":"10.4269\/ajtmh.12-0609","type":"journal-article","created":{"date-parts":[[2013,3,19]],"date-time":"2013-03-19T07:15:38Z","timestamp":1363677338000},"page":"937-939","source":"Crossref","is-referenced-by-count":13,"title":["Spotted Fever Group Rickettsia in Small Rodents from Areas of Low Endemicity for Brazilian Spotted Fever in the Eastern Region of Minas Gerais State, Brazil"],"prefix":"10.4269","volume":"88","author":[{"given":"Bruno S.","family":"Milagres","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda F.","family":"Padilha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos E.","family":"Montandon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata N.","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo B.","family":"Labruna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udio L.","family":"Mafra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio A. M.","family":"Galv\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Am J Clin Pathol","first-page":"669","article-title":"The pathology of fatal Mediterranean spotted fever","volume":"87","author":"Walker","year":"1987"},{"key":"R2","series-title":"Am J Trop Med Hyg","first-page":"1305","article-title":"Rickettsia in synanthropic and domestic animals and their hosts from two areas of low endemicity for Brazilian spotted fever in the eastern region of Minas Gerais, Brazil","volume":"83","author":"Milagres","year":"2010"},{"key":"R3","first-page":"1","article-title":"Towards more standardized methods in ecological studies of Rickettsiae in relation to their vectors and vertebrate hosts","author":"Rehacer","year":"1978"},{"key":"R4","series-title":"Am J Trop Med Hyg","first-page":"78","article-title":"Antigenic diversity of Rickettsia conorii","volume":"47","author":"Walker","year":"1992"},{"key":"R5","series-title":"Ecologia, Epidemiologia e Sociedade","author":"Forattini","year":"1992"},{"key":"R6","series-title":"Normas Operacionais de Centros de Controle de Zoonoses. 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