{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:23:16Z","timestamp":1790090596922,"version":"4.0.1"},"reference-count":73,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,6,5]]},"abstract":"<jats:p>A systematic literature review of cystic echinoccocosis (CE) frequency and symptoms was conducted. Studies without denominators, original data, or using one serological test were excluded. Random-effect log-binomial models were run for CE frequency and proportion of reported symptoms where appropriate. A total of 45 and 25 articles on CE frequency and symptoms met all inclusion criteria. Prevalence of CE ranged from 1% to 7% in community-based studies and incidence rates ranged from 0 to 32 cases per 100,000 in hospital-based studies. The CE prevalence was higher in females (Prevalence Proportion Ratio: 1.35 [95% Bayesian Credible Interval: 1.16\u20131.53]) and increased with age. The most common manifestations of hepatic and pulmonary CE were abdominal pain (57.3% [95% confidence interval [CI]: 37.3\u201376.1%]) and cough (51.3% [95% CI: 35.7\u201366.7%]), respectively. The results are limited by the small number of unbiased studies. Nonetheless, the age\/gender prevalence differences could be used to inform future models of CE burden.<\/jats:p>","DOI":"10.4269\/ajtmh.12-0692","type":"journal-article","created":{"date-parts":[[2013,4,2]],"date-time":"2013-04-02T01:54:12Z","timestamp":1364867652000},"page":"1011-1027","source":"Crossref","is-referenced-by-count":134,"title":["A Systematic Review of the Literature on Cystic Echinococcosis Frequency Worldwide and Its Associated Clinical Manifestations"],"prefix":"10.4269","volume":"88","author":[{"given":"Christine M.","family":"Budke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Carabin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick 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