{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:35:37Z","timestamp":1790278537249,"version":"4.1.0"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,6,5]]},"abstract":"<jats:p>We studied the value of an IgG Western blot (WB) with <jats:italic>Paragonimus kellicotti<\/jats:italic> (Pk) antigen for diagnosis of North American paragonimiasis. The test was evaluated with sera from patients with Pk and <jats:italic>Paragonimus westermani<\/jats:italic> infections, with control sera from patients with other helminth infections, and sera from healthy Americans. All 11 proven Pk infection sera and two samples from suspected cases that were negative by <jats:italic>P. westermani<\/jats:italic> WB at the Centers for Disease Control and Prevention (CDC) contained antibodies to antigens at 34 kDa and at 21\/23 kDa. Seven of 7 <jats:italic>P. westermani<\/jats:italic> sera contained antibodies to the 34 kDa antigen, but only 2 recognized the 21\/23 kDa doublet. No control samples were reactive with these antigens. Antibody reactivity declined after praziquantel treatment. Thus, the <jats:italic>P. kellicotti<\/jats:italic> WB appears to be superior to <jats:italic>P. westermani<\/jats:italic> WB for diagnosing Pk infections, and it may be useful for assessing responses to treatment.<\/jats:p>","DOI":"10.4269\/ajtmh.12-0720","type":"journal-article","created":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T01:42:41Z","timestamp":1366076561000},"page":"1035-1040","source":"Crossref","is-referenced-by-count":34,"title":["Serological Diagnosis of North American Paragonimiasis by Western Blot Using Paragonimus kellicotti Adult Worm Antigen"],"prefix":"10.4269","volume":"88","author":[{"given":"Peter U.","family":"Fischer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt C.","family":"Curtis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott 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