{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:59:15Z","timestamp":1761541155040},"reference-count":15,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7,10]]},"abstract":"<jats:p>Stevens-Johnson syndrome (SJS) is a severe form of erythema multiforme that primarily affects skin and mucous membranes. In Malawi, manifestations of SJS may become more common in human immunodeficiency virus\u2013infected patients receiving nevirapine-based antiretroviral therapy (ART) because the CD4 cell threshold for starting ART has increased from 250 to 350 cells\/\u03bcL. We describe a patient with severe ocular complications from SJS that developed soon after initiation of nevirapine-based ART and cotrimoxazole preventive treatment, which led to blindness. We draw attention to preventive measures that can potentially reduce permanent ocular damage from SJS.<\/jats:p>","DOI":"10.4269\/ajtmh.12-0761","type":"journal-article","created":{"date-parts":[[2013,4,9]],"date-time":"2013-04-09T01:35:47Z","timestamp":1365471347000},"page":"162-164","source":"Crossref","is-referenced-by-count":6,"title":["Severe Eye Complications from Stevens-Johnson Syndrome in a Human Immunodeficiency Virus\u2013Infected Patient in Malawi"],"prefix":"10.4269","volume":"89","author":[{"given":"Markus","family":"Schulze Schwering","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petros","family":"Kayange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joep J.","family":"van Oosterhout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin S.","family":"Spitzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Dermatology in General Medicine","first-page":"555","article-title":"Erythema multiforme","author":"Elias","year":"1989"},{"year":"2012","series-title":"Quarterly Report of the Antiretroviral Treatment Programme in Malawi with Results up to July 31, 2012","author":"Department of HIV and AIDS Ministry of Health","key":"R2"},{"key":"R3","series-title":"Curr HIV Res","first-page":"65","article-title":"Risk factors for nevirapine-associated rash among HIV-infected patients with low CD4 cell counts in resource-limited settings","volume":"6","author":"Kiertiburanakul","year":"2008"},{"key":"R4","series-title":"Am J Dis Child","first-page":"526","article-title":"A new eruptive fever associated with stomatitis and ophthalmia. 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