{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:06:35Z","timestamp":1783418795187,"version":"3.54.6"},"reference-count":22,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10,9]]},"abstract":"<jats:p>Laboratory-reared <jats:italic>Oropsylla montana<\/jats:italic> were exposed to soil and wild-caught <jats:italic>Oropsylla montana<\/jats:italic> feces for 1 week. Fleas from these two treatments and a control group of laboratory-reared fleas were infected with <jats:italic>Yersinia pestis<\/jats:italic>, the etiological agent of plague. Fleas exposed to soil transmitted <jats:italic>Y. pestis<\/jats:italic> to mice at a significantly greater rate (50.0% of mice were infected) than control fleas (23.3% of mice were infected). Although the concentration of <jats:italic>Y. pestis<\/jats:italic> in fleas did not differ among treatments, the minimum transmission efficiency of fleas from the soil and wild flea feces treatments (6.9% and 7.6%, respectively) were more than three times higher than in control fleas (2.2%). Our results suggest that exposing laboratory-reared fleas to diverse microbes alters transmission of <jats:italic>Y. pestis<\/jats:italic>.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0138","type":"journal-article","created":{"date-parts":[[2013,8,13]],"date-time":"2013-08-13T04:05:06Z","timestamp":1376366706000},"page":"784-787","source":"Crossref","is-referenced-by-count":7,"title":["Exposing Laboratory-Reared Fleas to Soil and Wild Flea Feces Increases Transmission of Yersinia pestis"],"prefix":"10.4269","volume":"89","author":[{"given":"Ryan T.","family":"Jones","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Vetter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth L.","family":"Gage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"PLoS Genet","first-page":"e1002272","article-title":"Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system","volume":"7","author":"Chandler","year":"2011"},{"key":"R2","series-title":"ISME J","first-page":"224","article-title":"Yersinia pestis infection and laboratory conditions alter flea-associated bacterial communities","volume":"7","author":"Jones","year":"2013"},{"key":"R3","series-title":"Microb Ecol","first-page":"349","article-title":"Bacterial communities associated with the digestive tract of the predatory ground beetle, Poecilus chalcites, and their modification by laboratory rearing and antibiotic treatment","volume":"57","author":"Lehman","year":"2009"},{"key":"R4","series-title":"Z Ang Entomol-J Appl Entomol","first-page":"337","article-title":"Microflora associated with wild and laboratory reared adult olive fruit flies, Dacus-oleae (GMEL)","volume":"96","author":"Tsiropoulos","year":"1983"},{"key":"R5","series-title":"J Appl Microbiol","first-page":"1390","article-title":"Comparison of the diversity of the bacterial communities in the intestinal tract of adult Bactrocera dorsalis from three different populations","volume":"110","author":"Wang","year":"2011"},{"key":"R6","series-title":"Trends Parasitol","first-page":"568","article-title":"Gut microbiota and parasite transmission by insect vectors","volume":"21","author":"Azambuja","year":"2005"},{"key":"R7","series-title":"Trends Parasitol","first-page":"514","article-title":"Microbiome influences on insect host vector competence","volume":"27","author":"Weiss","year":"2011"},{"key":"R8","series-title":"J Med Entomol","first-page":"758","article-title":"Reported cases of human plague infections in the United States, 1970\u20131991","volume":"30","author":"Craven","year":"1993"},{"key":"R9","series-title":"J Med Entomol","first-page":"737","article-title":"Studies of vector competency and efficiency of North American fleas for Yersinia pestis: state of the field and future research needs","volume":"46","author":"Eisen","year":"2009"},{"key":"R10","series-title":"Am J Trop Med Hyg","first-page":"552","article-title":"Quantitative competitive PCR as a technique for exploring flea - Yersinia pestis dynamics","volume":"62","author":"Engelthaler","year":"2000"},{"key":"R11","series-title":"Proc Natl Acad Sci USA","first-page":"15380","article-title":"Early-phase transmission of Yersinia pestis by unblocked fleas as a mechanism explaining rapidly spreading plague epizootics","volume":"103","author":"Eisen","year":"2006"},{"key":"R12","series-title":"PooledInfRate: a Microsoft Excel Add-In to Compute Prevalence Estimates from Pooled Samples","author":"Biggerstaff","year":"2006"},{"key":"R13","series-title":"Am J Trop Med Hyg","first-page":"949","article-title":"Early-phase transmission of Yersinia pestis by cat fleas (Ctenocephalides felis) and their potential role as vectors in a plague-endemic region of Uganda","volume":"78","author":"Eisen","year":"2008"},{"key":"R14","series-title":"J Med Entomol","first-page":"1160","article-title":"Demonstration of early-phase transmission of Yersinia pestis by the mouse flea, Aetheca wagneri (Siphonaptera: Ceratophylidae), and implications for the role of deer mice as enzootic reservoirs","volume":"45","author":"Eisen","year":"2008"},{"key":"R15","series-title":"J Med Entomol","first-page":"672","article-title":"Temporal dynamics of early-phase transmission of Yersinia pestis by unblocked fleas: secondary infectious feeds prolong efficient transmission by Oropsylla montana (Siphonaptera: Ceratophyllidae)","volume":"44","author":"Eisen","year":"2007"},{"key":"R16","series-title":"J Med Entomol","first-page":"678","article-title":"Early-phase transmission of Yersinia pestis by unblocked Xenopsylla cheopis (Siphonaptera: Pulicidae) is as efficient as transmission by blocked fleas","volume":"44","author":"Eisen","year":"2007"},{"key":"R17","series-title":"Vector Borne Zoonotic Dis","first-page":"359","article-title":"Oropsylla hirsuta (Siphonaptera: Ceratophyllidae) can support plague epizootics in black-tailed prairie dogs (Cynomys ludovicianus) by early-phase transmission of Yersinia pestis","volume":"8","author":"Wilder","year":"2008"},{"key":"R18","series-title":"EcoHealth","first-page":"205","article-title":"Transmission efficiency of two flea species (Oropsylla tuberculata cynomuris and Oropsylla hirsuta) involved in plague epizootics among prairie dogs","volume":"5","author":"Wilder","year":"2008"},{"key":"R19","series-title":"J Infect Dis","first-page":"18","article-title":"Sylvatic plague studies. II. The fate of Pasteurelia pestis in the flea","volume":"72","author":"Douglas","year":"1941"},{"key":"R20","series-title":"Plague in Rodents and Fleas in the Western Part of the United States","first-page":"83","author":"Eskey","year":"1940"},{"key":"R21","series-title":"J Infect Dis","first-page":"1907","article-title":"Poor vector competence of fleas and the evolution of hypervirulence in Yersinia pestis","volume":"191","author":"Lorange","year":"2005"},{"key":"R22","series-title":"J Infect Dis","first-page":"1","article-title":"Sylvatic plague studies. 5. The determination of vector efficiency","volume":"77","author":"Wheeler","year":"1945"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/89\/4\/article-p784.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/89\/4\/article-p784.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/89\/4\/article-p784.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T18:20:04Z","timestamp":1723054804000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/89\/4\/article-p784.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,9]]},"references-count":22,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0138","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,9]]}}}