{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:24:28Z","timestamp":1791293068941,"version":"4.1.0"},"reference-count":29,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,5,7]]},"abstract":"<jats:p>Q fever is an emergent disease in French Guiana. We compared the incidence clinical and serologic profiles between patients from Cayenne, French Guiana and Marseille in metropolitan France during a four-year period. The annual incidence of diagnosed acute Q fever was significantly higher in Cayenne (17.5\/100,000) than in Marseille (1.9\/100,000) (<jats:italic>P<\/jats:italic> = 0.0004), but not the annual incidence of endocarditis (1.29 versus 0.34\/100,000). Most patients had fever (97%) and pneumonia (83%) in Cayenne versus 81% and 8% in Marseille (<jats:italic>P<\/jats:italic> &lt; 0.0001 and <jats:italic>P<\/jats:italic> &lt; 0.0001, respectively) but transaminitis was more common in patients from Marseille (54% versus 32%; <jats:italic>P<\/jats:italic> &lt; 0.0001). The proportion of patients with cardiovascular infections was significantly lower in Cayenne (7%) than in Marseille (17%) (<jats:italic>P<\/jats:italic> = 0.017), although they showed a stronger immune response with higher levels of phase I IgG (<jats:italic>P<\/jats:italic> = 0.024). The differing epidemiology, clinical, and serologic responses of patients from Cayenne and Marseille suggest a different source of infection and a different strain of <jats:italic>Coxiella burnetii<\/jats:italic>.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0164","type":"journal-article","created":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T06:17:58Z","timestamp":1395123478000},"page":"915-919","source":"Crossref","is-referenced-by-count":39,"title":["Comparison between Emerging Q Fever in French Guiana and Endemic Q fever in Marseille, France"],"prefix":"10.4269","volume":"90","author":[{"given":"Sophie","family":"Edouard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aba","family":"Mahamat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magalie","family":"Demar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Abboud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Djossou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Raoult","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Lancet Infect Dis","first-page":"219","article-title":"Natural history and pathophysiology of Q fever","volume":"5","author":"Raoult","year":"2005"},{"key":"R2","series-title":"Clin Microbiol Rev","first-page":"518","article-title":"Q fever","volume":"12","author":"Maurin","year":"1999"},{"key":"R3","series-title":"Infect Dis Clin North Am","first-page":"505","article-title":"Q fever","volume":"22","author":"Tissot-Dupont","year":"2008"},{"key":"R4","series-title":"Clin Infect Dis","first-page":"489","article-title":"Q fever","volume":"20","author":"Raoult","year":"1995"},{"key":"R5","series-title":"Emerg Infect Dis","first-page":"1211","article-title":"Coxiella burnetii genotyping","volume":"11","author":"Glazunova","year":"2005"},{"key":"R6","series-title":"Ann N Y Acad Sci","first-page":"51","article-title":"Chronic Q fever: diagnosis and follow-up","volume":"590","author":"Raoult","year":"1990"},{"key":"R7","series-title":"J Infect","first-page":"102","article-title":"Chronic Q fever: expert opinion versus literature analysis and consensus","volume":"65","author":"Raoult","year":"2012"},{"key":"R8","series-title":"Transfusion","first-page":"144","article-title":"Coxiella burnetii infection among blood donors during the 2009 Q-fever outbreak in The Netherlands","volume":"52","author":"Hogema","year":"2012"},{"key":"R9","series-title":"J Clin Microbiol","first-page":"1823","article-title":"Diagnosis of Q fever","volume":"36","author":"Fournier","year":"1998"},{"key":"R10","series-title":"Publ Inst Pasteur Guyane Fr Inini","first-page":"1","article-title":"Q fever in French Guiana","volume":"18","author":"Floch","year":"1957"},{"key":"R11","series-title":"Emerg Infect Dis","first-page":"131","article-title":"Q fever in French Guiana: new trends","volume":"4","author":"Pfaff","year":"1998"},{"key":"R12","series-title":"Bull Epid\u00e9miol Hebd","article-title":"Fievre Q en Guyane: une \u00e9pid\u00e9miologie particuli\u00e8re","volume":"35","author":"Francois","year":"1997"},{"key":"R13","series-title":"J Infect Dis","first-page":"278","article-title":"Suburban transmission of Q fever in French Guiana: evidence of a wild reservoir","volume":"184","author":"Gardon","year":"2001"},{"key":"R14","series-title":"Bull Veille Sanit","article-title":"Epidemiologie de la fi\u00e8vre Q en Guyanne, 1990\u20132006","volume":"9","author":"Grangier","year":"2009"},{"key":"R15","series-title":"Clin Infect Dis","first-page":"67","article-title":"Q fever pneumonia in French Guiana: high prevalence, risk factors and prognostic score","volume":"55","author":"Epelboin","year":"2012"},{"key":"R16","series-title":"Clin Infect Dis","first-page":"131","article-title":"Comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases","volume":"51","author":"Fournier","year":"2010"},{"key":"R17","series-title":"Eur Respir J","first-page":"263","article-title":"Q fever pneumonia: a review of 164 community-acquired cases in the Basque country","volume":"2","author":"Sobradillo","year":"1989"},{"key":"R18","series-title":"FEMS Immunol Med Microbiol","first-page":"3","article-title":"The 2007\u20132010 Q fever epidemic in The Netherlands: characteristics of notified acute Q fever patients and the association with dairy goat farming","volume":"64","author":"Dijkstra","year":"2012"},{"key":"R19","series-title":"J Infect Dis","first-page":"484","article-title":"Route of infection determines the clinical manifestations of acute Q fever","volume":"173","author":"Marrie","year":"1996"},{"key":"R20","series-title":"Infect Immun","first-page":"2443","article-title":"Pathologic changes during acute Q fever: influence of the route of infection and inoculum size in infected guinea pigs","volume":"65","author":"La Scola","year":"1997"},{"key":"R21","series-title":"Medicine (Baltimore)","first-page":"109","article-title":"Q fever 1985\u20131998. Clinical and epidemiologic features of 1,383 infections","volume":"79","author":"Raoult","year":"2000"},{"key":"R22","series-title":"Infect Immun","first-page":"2469","article-title":"Q fever pneumonia: virulence of Coxiella burnetii pathovars in a murine model of aerosol infection","volume":"73","author":"Stein","year":"2005"},{"key":"R23","series-title":"Infect Immun","first-page":"5640","article-title":"Coxiella burnetii isolates cause genogroup-specific virulence in mouse and guinea pig models of acute Q fever","volume":"77","author":"Russell-Lodrigue","year":"2009"},{"key":"R24","series-title":"Infect Immun","first-page":"1144","article-title":"Comparative virulence of intra- and interstrain lipopolysaccharide variants of Coxiella burnetii in the guinea pig model","volume":"55","author":"Moos","year":"1987"},{"key":"R25","series-title":"Acta Virol","first-page":"437","article-title":"Comparison of virulence for guinea pigs and mice of different Coxiella burnetii phase I strains","volume":"37","author":"Kazar","year":"1993"},{"key":"R26","series-title":"Eur J Clin Microbiol Infect Dis","first-page":"361","article-title":"Q fever and pregnancy: disease, prevention, and strain specificity","volume":"32","author":"Angelakis","year":"2012"},{"key":"R27","series-title":"Int J Epidemiol","first-page":"282","article-title":"An important outbreak of human Q fever in a Swiss Alpine valley","volume":"16","author":"Dupuis","year":"1997"},{"key":"R28","series-title":"Emerg Infect Dis","first-page":"350","article-title":"Q fever in France, 1985\u20132009","volume":"17","author":"Frankel","year":"2011"},{"key":"R29","series-title":"Am J Epidemiol","first-page":"662","article-title":"Mapping disease incidence in suburban areas using remotely sensed data","volume":"156","author":"Tran","year":"2002"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/5\/article-p915.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/5\/article-p915.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/90\/5\/article-p915.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:26:11Z","timestamp":1723065971000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/90\/5\/article-p915.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,7]]},"references-count":29,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.13-0164","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,7]]}}}