{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T21:24:38Z","timestamp":1790457878246,"version":"4.1.0"},"reference-count":61,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,3,5]]},"abstract":"<jats:p>Lyme disease (<jats:italic>Borrelia burgdorferi<\/jats:italic> infection) is the most common vector-transmitted disease in the United States. The majority of human Lyme disease (LD) cases occur in the summer months, but the timing of the peak occurrence varies geographically and from year to year. We calculated the beginning, peak, end, and duration of the main LD season in 12 highly endemic states from 1992 to 2007 and then examined the association between the timing of these seasonal variables and several meteorological variables. An earlier beginning to the LD season was positively associated with higher cumulative growing degree days through Week 20, lower cumulative precipitation, a lower saturation deficit, and proximity to the Atlantic coast. The timing of the peak and duration of the LD season were also associated with cumulative growing degree days, saturation deficit, and cumulative precipitation, but no meteorological predictors adequately explained the timing of the end of the LD season.<\/jats:p>","DOI":"10.4269\/ajtmh.13-0180","type":"journal-article","created":{"date-parts":[[2014,1,28]],"date-time":"2014-01-28T05:47:03Z","timestamp":1390888023000},"page":"486-496","source":"Crossref","is-referenced-by-count":54,"title":["Meteorological Influences on the Seasonality of Lyme Disease in the United States"],"prefix":"10.4269","volume":"90","author":[{"given":"Sean M.","family":"Moore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca 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1992\u20132006","volume":"57","author":"Bacon","year":"2008"},{"key":"R4","series-title":"Ecology and Environmental Management of Lyme disease","first-page":"25","article-title":"Population ecology of Ixodes dammini","author":"Fish","year":"1993"},{"key":"R5","series-title":"Science","first-page":"1610","article-title":"The biological and social phenomenon of Lyme-disease","volume":"260","author":"Barbour","year":"1993"},{"key":"R6","series-title":"J Med Entomol","first-page":"622","article-title":"Investigation of relationships between temperature and developmental rates of tick Ixodes scapularis (Acari: Ixodidae) in the laboratory and field","volume":"41","author":"Ogden","year":"2004"},{"key":"R7","series-title":"Exp Appl Acarol","first-page":"695","article-title":"Field and laboratory studies on the timing of oviposition and hatching of the western black-legged tick, Ixodes pacificus (Acari: Ixodidae)","volume":"20","author":"Peavey","year":"1996"},{"key":"R8","series-title":"Int J Parasitol","first-page":"979","article-title":"An empirical quantitative framework for the seasonal population dynamics of the tick Ixodes ricinus","volume":"32","author":"Randolph","year":"2002"},{"key":"R9","series-title":"Parasitology","first-page":"S37","article-title":"Tick ecology: processes and patterns behind the epidemiological risk posed by ixodid ticks as vectors","volume":"129","author":"Randolph","year":"2004"},{"key":"R10","series-title":"J Med Entomol","first-page":"1025","article-title":"Air temperature and relative humidity effects on behavioral activity of blacklegged tick (Acari: Ixodidae) nymphs in New Jersey","volume":"35","author":"Vail","year":"1998"},{"key":"R11","series-title":"J Med Entomol","first-page":"842","article-title":"Vertical movement and posture of blacklegged tick (Acari: Ixodidae) nymphs as a function of temperature and relative humidity in laboratory experiments","volume":"39","author":"Vail","year":"2002"},{"key":"R12","series-title":"J Med Entomol","first-page":"395","article-title":"Meteorologically mediated diurnal questing of Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) nymphs","volume":"40","author":"Schulze","year":"2003"},{"key":"R13","series-title":"J Exp Biol","first-page":"1809","article-title":"Darkness induces mobility, and saturation deficit limits questing duration, in the tick Ixodes ricinus","volume":"206","author":"Perret","year":"2003"},{"key":"R14","series-title":"Am J Med","first-page":"S2","article-title":"Environmental risk and prevention of Lyme-disease","volume":"98","author":"Fish","year":"1995"},{"key":"R15","series-title":"N Engl J Med","first-page":"2424","article-title":"Current concepts\u2014How can we prevent Lyme disease?","volume":"348","author":"Hayes","year":"2003"},{"key":"R16","series-title":"Annu Rev Entomol","first-page":"323","article-title":"Prevention of tick-borne diseases","volume":"53","author":"Piesman","year":"2008"},{"issue":"(Suppl 40)","key":"R17","series-title":"Int J Med Microbiol","first-page":"17","article-title":"Strategies for reducing the risk of Lyme borreliosis in North America","volume":"296","author":"Piesman","year":"2006"},{"key":"R18","series-title":"J Med Entomol","first-page":"344","article-title":"Efficacy of granular deltamethrin against Ixodes scapularis and Amblyomma americanum (Acari: Ixodidade) nymphs","volume":"38","author":"Schulze","year":"2001"},{"key":"R19","series-title":"J Med Entomol","first-page":"695","article-title":"Trial of a minimal-risk botanical compound to control the vector tick of Lyme disease","volume":"47","author":"Rand","year":"2010"},{"key":"R20","series-title":"J Econ Entomol","first-page":"123","article-title":"Effects of an application of granular carbaryl on nontarget forest floor arthropods","volume":"94","author":"Schulze","year":"2001"},{"key":"R21","series-title":"Vector Borne Zoonotic Dis","first-page":"769","article-title":"Knowledge, attitudes, and behaviors regarding Lyme disease prevention among Connecticut residents, 1999\u20132004","volume":"8","author":"Gould","year":"2008"},{"key":"R22","series-title":"J Econ Entomol","first-page":"2316","article-title":"Ability of two natural products, nootkatone and carvacrol, to suppress Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) in a Lyme disease endemic area of New Jersey","volume":"102","author":"Dolan","year":"2009"},{"key":"R23","series-title":"J Econ Entomol","first-page":"659","article-title":"Suppression of host-seeking Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) nymphs after dual applications of plant-derived acaricides in New Jersey","volume":"104","author":"Jordan","year":"2011"},{"key":"R24","series-title":"Am J Prev Med","first-page":"201","article-title":"Peridomestic Lyme disease prevention: results of a population-based case-control study","volume":"37","author":"Connally","year":"2009"},{"key":"R25","series-title":"Ann Intern Med","first-page":"22","article-title":"Treatment of the early manifestations of Lyme disease","volume":"99","author":"Steere","year":"1983"},{"key":"R26","series-title":"N Engl J Med","first-page":"2794","article-title":"Clinical practice. Early Lyme disease","volume":"354","author":"Wormser","year":"2006"},{"key":"R27","series-title":"J Appl Ecol","first-page":"1029","article-title":"Modelling the effects of recent changes in climate, host density and acaricide treatments on population dynamics of Ixodes ricinus in the UK","volume":"48","author":"Dobson","year":"2011"},{"key":"R28","series-title":"Environ Health Perspect","first-page":"99","article-title":"El Nino and the dynamics of vectorborne disease transmission","volume":"107","author":"Hales","year":"1999"},{"key":"R29","series-title":"Malar J","first-page":"32","article-title":"A weather-driven model of malaria transmission","volume":"3","author":"Hoshen","year":"2004"},{"key":"R30","series-title":"Ecol Lett","first-page":"467","article-title":"Seasonality and the dynamics of infectious diseases","volume":"9","author":"Altizer","year":"2006"},{"key":"R31","series-title":"Am J Epidemiol","first-page":"531","article-title":"Effects of climate on variability in Lyme disease incidence in the northeastern United States","volume":"157","author":"Subak","year":"2003"},{"key":"R32","series-title":"MMWR","first-page":"1","article-title":"Summary of notifiable diseases: United States, 2007","volume":"56","author":"Centers for Disease Control, Prevention","year":"2009"},{"key":"R33","series-title":"MMWR Recomm Rep","first-page":"1","article-title":"Case definitions for infectious conditions under public health surveillance","volume":"46","author":"Centers for Disease Control, Prevention","year":"1997"},{"key":"R34","series-title":"J Geophys Res, D, Atmospheres","article-title":"Continental-scale water and energy flux analysis and validation for the North American Land Data Assimilation System project phase 2 (NLDAS-2): 1. Intercomparison and application of model products","volume":"117","author":"Xia","year":"2012"},{"key":"R35","series-title":"J Geophys Res, D, Atmospheres","article-title":"Real-time and retrospective forcing in the North American Land Data Assimilation System (NLDAS) project","volume":"108","author":"Cosgrove","year":"2003"},{"key":"R36","series-title":"J Geophys Res, D, Atmospheres","article-title":"The multi-institution North American Land Data Assimilation System (NLDAS): utilizing multiple GCIP products and partners in a continental distributed hydrological modeling system","volume":"108","author":"Mitchell","year":"2004"},{"key":"R37","series-title":"Bull Am Meteorol Soc","first-page":"343","article-title":"North American regional reanalysis","volume":"87","author":"Mesinger","year":"2006"},{"key":"R38","series-title":"Am J Trop Med Hyg","first-page":"632","article-title":"Predicting density of Ixodes pacificus nymphs in dense woodlands in Mendocino County, California, based on geographic information systems and remote sensing versus field-derived data","volume":"74","author":"Eisen","year":"2006"},{"key":"R39","series-title":"Ticks Tick Borne Dis","first-page":"35","article-title":"A spatially-explicit model of acarological risk of exposure to Borrelia burgdorferi-infected Ixodes pacificus nymphs in northwestern California based on woodland type, temperature, and water vapor","volume":"1","author":"Eisen","year":"2010"},{"key":"R40","article-title":"Leaps: regression subset selection (using Fortran code by Alan Miller). R package version 2.9","author":"Lumley","year":"2009"},{"key":"R41","article-title":"lme4: linear mixed-effects models using Eigen and S4. R package version 1.0-5","author":"Bates","year":"2013"},{"key":"R42","series-title":"J Med Entomol","first-page":"143","article-title":"Survival and development of Ixodes-scapularis (Acari, Ixodidae) under various climatic conditions in Ontario, Canada","volume":"32","author":"Lindsay","year":"1995"},{"key":"R43","series-title":"Med Vet Entomol","first-page":"235","article-title":"Seasonal activity patterns of Ixodes pacificus nymphs in relation to climatic conditions","volume":"16","author":"Eisen","year":"2002"},{"key":"R44","series-title":"Wien Klin Wochenschr","first-page":"473","article-title":"Biology of Ixodes species ticks in relation to tick-borne zoonoses","volume":"114","author":"Gray","year":"2002"},{"key":"R45","series-title":"Revue Scientifique Et Technique-Office International Des Epizooties","first-page":"367","article-title":"Dynamics of tick-borne disease systems: minor role of recent climate change","volume":"27","author":"Randolph","year":"2008"},{"key":"R46","series-title":"Med Vet Entomol","first-page":"25","article-title":"Abiotic and biotic determinants of the seasonal dynamics of the tick Rhipicephalus appendiculatus in South Africa","volume":"11","author":"Randolph","year":"1997"},{"key":"R47","series-title":"Trop Anim Health Prod","first-page":"153","article-title":"Observations on the development and survival of the ixodid tick Rhipicephalus appendiculatus Neumann, 1901 under quasi-natural conditions in Kenya","volume":"5","author":"Branagan","year":"1973"},{"key":"R48","series-title":"Appl Environ Microbiol","first-page":"2476","article-title":"Climate and tick seasonality are predictors of Borrelia burgdorferi genotype distribution","volume":"75","author":"Gatewood","year":"2009"},{"key":"R49","series-title":"J Appl Ecol","first-page":"1017","article-title":"A modified matrix model to describe the seasonal population ecology of the European tick Ixodes ricinus","volume":"48","author":"Dobson","year":"2011"},{"key":"R50","series-title":"Int J Med Microbiol","first-page":"19","article-title":"Ixodes ricinus seasonal activity: implications of global warming indicated by revisiting tick and weather data","volume":"298","author":"Gray","year":"2008"},{"key":"R51","series-title":"Parasitol Res","first-page":"554","article-title":"Influence of saturation deficit and temperature on Ixodes ricinus tick questing activity in a Lyme borreliosis-endemic area (Switzerland)","volume":"86","author":"Perret","year":"2000"},{"key":"R52","series-title":"Bull Entomol Res","first-page":"69","article-title":"Age structure of a population of Ixodes ricinus (Acari: Ixodidae) in relation to its seasonal questing","volume":"91","author":"Walker","year":"2001"},{"key":"R53","series-title":"Int J Parasitol","first-page":"513","article-title":"Modelling the effect of temperature variation on the seasonal dynamics of Ixodes ricinus tick populations","volume":"41","author":"Hancock","year":"2011"},{"key":"R54","series-title":"J Med Entomol","first-page":"684","article-title":"Life cycle of Ixodes pacificus (Acari: Ixodidae): timing of developmental processes under field and laboratory conditions","volume":"38","author":"Padgett","year":"2001"},{"key":"R55","series-title":"Bull Entomol Res","first-page":"263","article-title":"The development and questing activity of Ixodes-ricinus (L) (Acari, Ixodidae) under field conditions in Ireland","volume":"72","author":"Gray","year":"1982"},{"key":"R56","series-title":"Physiology of Ticks","first-page":"469","article-title":"Diapause and biological rhythms in ticks","author":"Belozerov","year":"1982"},{"key":"R57","series-title":"Folia Parasitol (Praha)","first-page":"314","article-title":"Nymphal diapause and its photoperiodic control in the tick Ixodes scapularis (Acari: Ixodidae)","volume":"49","author":"Belozerov","year":"2002"},{"key":"R58","series-title":"J Med Entomol","first-page":"741","article-title":"Impact of microclimate on immature tick-rodent host interactions (Acari: Ixodidae): implications for parasite transmission","volume":"36","author":"Randolph","year":"1999"},{"key":"R59","series-title":"Annu Rev Public Health","first-page":"127","article-title":"Seasonality of infectious diseases","volume":"28","author":"Fisman","year":"2007"},{"key":"R60","series-title":"Environ Health Perspect","first-page":"1152","article-title":"A climate-based model predicts the spatial distribution of the Lyme disease vector Ixodes scapularis in the United States","volume":"111","author":"Brownstein","year":"2003"},{"key":"R61","series-title":"J Theor Biol","first-page":"621","article-title":"Projected effects of climate change on tick phenology and fitness of pathogens transmitted by the North American tick Ixodes scapularis","volume":"254","author":"Ogden","year":"2008"}],"container-title":["The American Society of Tropical Medicine and 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